Chitosan-thio-amidine conjugates and their cosmetic as well...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S054000, C536S055100, C536S020000, C536S055300

Reexamination Certificate

active

07053068

ABSTRACT:
By the reaction of chitosan with iminothiolactones such as 2-iminothiolane, thiol groups can be covalently immobilized on the polymer. The resulting chitosan derivatives exhibit thiol groups which are capable of forming inter- and intramolecular disulfide bonds. Because of this crosslinking process the viscosity of polymer solutions is strongly improved. Moreover, the cationic character of the polymer is strongly improved. Preferred applications of these novel chitosan derivatives are their cosmetic and pharmaceutical use

REFERENCES:
patent: 5248772 (1993-09-01), Siiman et al.
patent: 3432227 (1986-03-01), None
patent: 0 665 022 (1995-08-01), None
patent: WO 95/22315 (1995-08-01), None
patent: WO 98/31712 (1998-07-01), None
patent: WO 00/71136 (2000-11-01), None
patent: WO 00/71180 (2000-11-01), None
patent: WO 01/55220 (2001-08-01), None
Alejandro et al., “Activation of polysaccharides with 2-iminothiolane and its uses,”Biochemistry, 19:4341-4345, 1980.
Illum, “Chitosan and its use as pharmaceutical excipient,”Pharmaceutical Research, 15(9):1326-1331, 1998.
Naidoo, “Natural cosmetic constituents: seaweed, chitosan and rice,”South African Pharmaceutical Journal, 59(6):131-132, 1992.
Tarentino et al., “2-iminothiolane: a reagent for the introduction of sulphydryl groups into oligosaccharides derived from asparagine-linked glycans,”Glycobiology, 3(3):279-285, 1993.
Thanou et al., “Mono-N-carboxymethyl chitosan (MCC), a polyampholytic chtosan derivative, enhances the intestinal absorption of low molecular weight heparin across intestinal epithelia in vitro and in vivo,”J. Pharm. Sci., 90(1):38-46, 2001.
Thanou et al., “N-Trimethylated chitosan chloroide (TMC) improves the intestinal permeation of the peptide drug Buserelin invitro (Caco-2 cells) and in vivo (rats),”Pharmaceutical Research, 17(1):27-31, 2000.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Chitosan-thio-amidine conjugates and their cosmetic as well... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Chitosan-thio-amidine conjugates and their cosmetic as well..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chitosan-thio-amidine conjugates and their cosmetic as well... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3630911

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.