Chiral separations by simulated moving bed chromatography operat

Details Chiral separations by simulated moving bed chromatography operat Chiral separations by simulated moving bed chromatography operat

1995-02-13

1996-05-21

Therkorn, Ernest G.

Liquid purification or separation

Processes

Chromatography

2101982, B01D 1508

Patent

active

055186254

ABSTRACT:
Resolution of a racemic mixture of organic materials by simulated moving bed chromatography using a chiral stationary phase can be routinely effected at atypically low values of k' with recoveries of at least 95% and an optical purity of at least 95%. In particular, values in the range 0.1<k'<1.0 are recommended with a resulting savings in mobile phase consumption, inventory, and recovery.

REFERENCES:
patent: 5126055 (1992-06-01), Yamashita
patent: 5407580 (1995-04-01), Hester
patent: 5433793 (1995-07-01), Herber
patent: 5434298 (1995-07-01), Negawa
patent: 5434299 (1995-07-01), Negawa

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