Chiral intermediates for the preparation of carbacephems

Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...

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C07D47104, C07D41304, C07B 4304

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active

057009333

ABSTRACT:
The present invention is directed to azetidinone compounds of the following formula: ##STR1## which are useful as intermediates to carbacephalosporins: ##STR2## These carbacephalosporins are useful as antibacterials.

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Caputo, et al., "The Oxidation of Cyclobutanols and Aromatic Rings with Ruthenium Tetroxide, " 47 Tetrahedron Letters pp. 4729-4731 (1967).
Klein, et al., "Umsetzung Adsorbierter Aromaten Mit Ozon," 48 Tetrahedron Letters 4249-4250 (1975).
Deno, et al., "Aromatic Ring Oxidation of Alkylbenzene," 20 Tetrahedron Letters 1703-1704 (1977).

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