Chiral intermediate, process for producing the same and its...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Reexamination Certificate

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07982058

ABSTRACT:
The compound of formula (I): is provided. It may be produced by subjecting a compound of formula (IV) to a reduction reaction wherein R represents hydrogen, straight or branched C1-C6alkyl. This compound is a valuable intermediate which may be used in the synthesis of fesoterodine, tolterodine, its active metabolite, and related compounds.

REFERENCES:
patent: 6713464 (2004-03-01), Meese et al.
patent: 6858650 (2005-02-01), Meese
patent: 2009/0306384 (2009-12-01), Ahman et al.
patent: 89/06644 (1989-07-01), None
patent: 94/11337 (1994-05-01), None
patent: 98/43942 (1998-10-01), None
patent: 01/49649 (2001-07-01), None
patent: 01/96279 (2001-12-01), None
March's Advanced Organic Chemistry, 5th Ed., a Wiley-Interscience Publication, 2001, pp. 1514-1519.
Walker, “The Functional Group Selectivity of Complex Hydride Reducing Agents.” Chem. Soc. Rev. 5, 1976, pp. 23-50.
Soai et al., “Mixed Solvents Containing Methanol as Useful Reaction Media for Unique Chemoselective Reductions Within Lithium Borohydride.” J. Org. Chem. 51, 1986, pp. 4000-4005.

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