Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1997-09-23
1999-01-05
Powers, Fiona T.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
546245, 564123, 564170, 564201, C07D29516
Patent
active
058565191
ABSTRACT:
This invention relates to a method for the stereoselective synthesis of a 2-aryloxycarboxylic acid using a chiral auxiliary to enhance the stereoselectivity of the alkylation of the .alpha.-halo acid with an aryloxy group.
REFERENCES:
patent: 4192892 (1980-03-01), Thorsell et al.
patent: 4222960 (1980-09-01), Wechsberg et al.
patent: 4622415 (1986-11-01), Forster et al.
patent: 5622971 (1997-04-01), Winn et al.
Koh, K., et al., J. of Organic Chem., vol. 59(16), pp. 4683-4686, 1994.
Larsen, R.D., et al., J. Am. Chem. Soc., vol. 111(19), pp. 7650-7653, 1989.
Koh, K., et al., Tetrahedron Letters, vol. 35(3), pp. 375-378, 1994.
Koh, K., et al., Tetrahedron Letters, vol. 34(28), pp. 4473-4476, 1993.
Devine, P.N., et al., Tetrahedron Letters, vol. 37(16), pp. 2683-2686, 1996.
Durst, T., et al., Tetrahedron Letters, vol. 33(45), pp. 6799-6802, 1992.
Terajima et al., Chemical Abstracts, 111:96967 (1989).
Ehrhart et al., Chemical Abstracts, 56:15362a-d (1962).
Takahashi et al., Chemical Abstracts, 120:216993 (1994).
Smith et al., Chemical Abstracts, 86:5104, (1977).
Adam et al., Synthesis, 1994, 6, 563-566.
Davis et al., J. Org. Chem., 1986, 51, 2402-2404.
Julia et al., Bull Soc. Chim. Fr., 1996, 133, 15-24.
Schurig et al., J. Organomet. Chem., 370 (1989) 81-96.
Toyooka et al., Heterocycles, 29(5), 1989, 975-978.
Devine Paul N.
Heid, Jr. Richard M.
Tschaen David M.
Camara Valerie J.
Daniel Mark R.
Garcia-Rivas J. Antonio
Merck & Co. , Inc.
Powers Fiona T.
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