Chiral 3-carbamoylmethyl-5-methyl hexanoic acids, key...

Details Chiral 3-carbamoylmethyl-5-methyl hexanoic acids, key... Chiral 3-carbamoylmethyl-5-methyl hexanoic acids, key...

2007-08-21

2008-12-30

Sullivan, Daniel M (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

C435S128000, C546S248000, C558S441000

Reexamination Certificate

active

07470812

ABSTRACT:
The invention encompasses the synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid, (S)-Pregabalin, via the intermediate, (3R)-5-methyl-3-(2-oxo-2{[(1R)-1-phenylethyl]amino}ethyl)hexanoic acid.

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