Chiral 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and prec

Details Chiral 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and prec Chiral 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and prec

1988-10-27

1990-03-27

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546 90, 549441, 560 12, 560 17, 560 29, 560 33, 560 39, 560 41, 562430, 562442, 562455, C07D21716

Patent

active

049122215

ABSTRACT:
The instant invention relates to optically pure, L-(S)forms of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid compounds and their method of preparation from optionally pure L-phenylalanine precursor compounds and their preparation utilizing novel in situ cationic catalyst systems.

REFERENCES:
patent: 4294832 (1981-10-01), Yoneda et al.
patent: 4344949 (1982-08-01), Hoefle et al.

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