Chimeric papillomavirus-like particles

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof

Reexamination Certificate

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C424S192100, C435S006120

Reexamination Certificate

active

07462356

ABSTRACT:
The present invention provides a papillomavirus-like particle, characterized as having conformational epitopes, comprising a papillomavirus L1 product and a papillomavirus L2 fusion product; and related synthetic DNA molecules, host cells, methods and vaccines.

REFERENCES:
patent: 5437951 (1995-08-01), Lowy et al.
patent: 5618536 (1997-04-01), Lowy et al.
patent: 5709996 (1998-01-01), Lowy et al.
patent: 5716620 (1998-02-01), Lowy et al.
patent: 5744142 (1998-04-01), Lowy et al.
patent: 5756284 (1998-05-01), Lowy et al.
patent: 5855891 (1999-01-01), Lowy et al.
patent: 5871998 (1999-02-01), Lowy et al.
patent: 5985610 (1999-11-01), Lowy et al.
patent: 7220419 (2007-05-01), Lowy et al.
patent: 2006/0269954 (2006-11-01), Lowy et al.
patent: WO 93/00436 (1993-01-01), None
patent: WO 93/02184 (1993-02-01), None
patent: WO 94/05792 (1994-03-01), None
patent: WO 96/11272 (1996-04-01), None
patent: WO 96/11274 (1996-04-01), None
patent: WO 97/46693 (1997-12-01), None
Alloub, et al., (1989) “Human papillomavirus infection and cervical intraepithelial neoplasia in women with renal allografts,”Br. Med. Journal298:153-156.
Baker, et al. (1991) “Structure of bovine and human papillomaviruses,”Biophys. J. 60:1445-1456.
Borisova, et al. (1989) “Recombinant core particles of hepatitis B virus exposing foreign antigenic determinants on their surface,”FEBS Lett. 259:121-124.
Brown, et al. (1994) “Chimeric parvovirus B19 capsids for the presentation of foreign epitopes,”Virology198:477-488.
Chen, et al. (1991) “Human papillomavirus type 16 nucleoprotein E7 is a tumor rejection antigen,”PNAS USA88:110-114.
Christensen, et al. (1990) “Antibody-Mediated neutralization in vivo of infectious papillomaviruses,”J. Virology64(7):3151-3156.
Christensen, et al. (1993) “Monoclonal antibody neutralization of BPV-1,”Virus Research28:195-202.
Christensen, et al. (1990) “Monoclonal antibody-mediated neutralization of infectious human papillomavirus type 11,”J. Virology64:5678-5681.
Christensen, et al. (1991) “The open reading frame L2 of cottontail rabbit papillomavirus contains antibody-inducing neutralizing epitopes,”Virology181:572-579.
Crawford, L. (1993) “Prospects for cervical cancer vaccines,”In Cancer Surveys16:215-229.
Dvoretzky, et al. (1980) “A quantitative in vitro focus assay for bovine papilloma virus,”Virology103:369-375.
Feltkemp, et al. (1993) “Vaccination with cytotoxic T lymphocyte epitope-containing peptide protects against a tumor induced by human papillomavirus type 16-transformed cells,”Eur. J. Immunol. 23:2242-2249.
Francis, et al. (1990) “Immunological properties of hepatitis B core antigen fusion proteins,”PNAS USA87:2545-2549.
Griffiths, et al. (1991) “Induction of high-titer neutralizing antibodies, using hybrid human immunodeficiency virus V3-Ty viruslike particles in a clinically relevant adjuvant,”J. Virology65:450-456.
Hagensee, et al. (1993) “Self-assembly of human papillomavirus type 1 capsids by expression of the L1 protein alone or by coexpression of the L1 and L2 capsid proteins,”J. Virology67:315-322.
Hartig, P.C. (1991) “Generation of recombinant baculovirus via liposome-mediated transfection,”Biotechniques11:310-312.
Higuchi, R. (1990) “Recombinant PCR. PCR Protocols; A guide to methods and applications,” p. 177.
Howley, P.M. (1990) “Papillomavirinae and their replication,” InVirology. 2d Edition (Fields, B.N. & Knipe, D.M.; eds.) p. 1627.
Kirnbauer, et al. (1994) “A virus-like particle enzyme-linked immunosorbent assay detects serum antibodies in a majority of women infected with human papillomavirus type 16,”J. National Cancer Institute86:494-499.
Kirnbauer, R. et al. (1994) “A vaccine of virus-like particles made in insect cells can inhibit papillomavirus infection of rabbits,” 13th International Papillomavirus Conference, Amsterdam, The Netherlands.
Kirnbauer, et al. (1993) “Efficient self-assembly of human papillomavirus type 16 L1 and L1-L2 into virus-like particles,”J. Virology67:6929-6936.
Kirnbauer, et al. (1992) “Papillomavirus L1 major capsid protein self-assembles into virus-like particles that are highly immunogenic,”PNAS USA89:12180-12184.
Koechel, et al. (1991) “Occurence of Antibodies to L1, L2, E4 and E7 Gene Products of Human Papillomavirus Types 6b, 16 and 18 Among Cervical Cancer Patients and Controls,”Int. J. Cancer48(5):682-688.
Laga, et al. (1992) “Genital papillomavirus infection and cervical dysplasia-opportunistic complications of HIV infection,”Int. J. Cancer50:45-48.
Michel, et al. (1990) “T- and B-lymphocyte responses to human immunodeficiency virus (HIV) type 1 in macaques immunized with hybrid HIV/hepatitis B surface antigen particles,”J. Virology64:2452-2455.
Miyamura, et al. (1994) “Parvovirus particles as platforms for protein presentation,”PNAS USA91:8507-8511.
Mose Larson, et al. (1987) “Proteins present in bovine papillomavirus particles,”J. Virology61:3596-3601.
Pilacinski, et al. (1984) “Cloning and expression inEscherichia coliof the bovine papillomavirus L1 and L2 open reading frames,”Biotechnology2:356-360.
Pushko, et al., (1994) “Sequence variation in the capsid protein genes of human papillomavirus type 16,”J. General Virol. 75: 911-916.
Roden, et al. (1994) “Interaction of papillomavirus with the cell surface,”J. Virology68:7260.
Rose, et al. (1993) “Expression of human papillomavirus type 11 L1 protein in insect cells: in vivo and in vitro assembly of viruslike particles,”J. Virology67:1936-1944.
Schiffman, M.H. (1992) “Recent progress in defining the epidemiology of human papillomavirus infection and cervical neoplasia,”J. Natl. Cancer Inst.84:394-398.
Segre, et al. (1955) “Neutralization of bovine papilloma virus with serums from cattle and horse with experimental papillomas,”Am. J. Vet. Res. 16:517-520.
Summers, et al. (1987) “A manual of methods for baculovirus vectors and insect cell culture procedures,” Texas Agricultural Experiment Station Bulletin vol. 1555.
Tindle, et al. (1994) “Chimeric hepatitis B core antigen particles containing B- and Th-epitopes of human papillomavirus type 16 E7 protein induce specific antibody and T-helper responses in immunised mice,”Virology200:547-557.
Viscidi, et al. (1993) “Serologic response in human papillomavirus-associated invasive cervical cancer,”Int. J. Cancer55:780-784.
Zhou, J. et al. (1992) “Definition of linear antigenic regions of the HPV16L1 capsid protein using synthetic virion-like particles,”Virology189: 592-599.
Zur Hausen, H. (1991) “Viruses in human cancers,”Science254:1167-1173.

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