Chimeric MHC class I antigens for inducing allograft tolerance

Details Chimeric MHC class I antigens for inducing allograft tolerance Chimeric MHC class I antigens for inducing allograft tolerance

1997-04-15

2000-04-18

Cunningham, Thomas M.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Fusion protein or fusion polypeptide

4241851, 4241931, 435 693, 530300, 530350, 530395, 530868, A61K 39385, C07K 14705, C07K 14745

Patent

active

060512326

ABSTRACT:
Chimeric MHC Class I molecules having a recipient-type N-terminus, a donor-type alpha-1 helical region, and a recipient-type alpha-2 domain induce tolerance to donor grafts when administered to the recipient at time of transplantation.

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