Chimeric kidney

Details Chimeric kidney Chimeric kidney

1997-02-11

1999-11-02

Stanton, Brian R.

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

435375, A61K 4800, A01N 102

Patent

active

059765240

ABSTRACT:
Methods for increasing the nephron mass of a mammalian recipient are disclosed. A metanephros from an allogenic or xenogeneic mammalian donor is implanted next to a recipient's omentum or under the renal capsule of the recipient's kidney. The metanephros becomes vascularized by the recipient's blood vessels, forming a chimeric kidney that produces urine and develops a ureter that facilitates externalization of the urine. A ureter to ureter anastomosis can be subsequently performed to provide fluid communication between the chimeric kidney ureter and a ureter of the recipient.

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