Chimeric histone acetyltransferase polypeptides

Details Chimeric histone acetyltransferase polypeptides Chimeric histone acetyltransferase polypeptides

2007-09-04

2007-09-04

Qian, Celine (Department: 1636)

Chemistry: molecular biology and microbiology

Vector, per se

C536S023400, C536S023600, C536S023740

Reexamination Certificate

active

10177478

ABSTRACT:
Chimeric polypeptides are disclosed that comprise a first polypeptide segment having histone acetyltransferase enzymatic activity and a second polypeptide segment that is similar to a subunit of a chromatin-associated histone deacetyltransferase protein complex. Also disclosed are nucleic acids encoding such chimeric polypeptides and eukaryotic organisms expressing such chimeric polypeptides.

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