Chimeric antigen-specific t cell-activating polypeptides

Details Chimeric antigen-specific t cell-activating polypeptides Chimeric antigen-specific t cell-activating polypeptides

2002-05-20

2010-11-30

Nickol, Gary B. (Department: 1646)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C530S300000, C530S350000, C514S002600

Reexamination Certificate

active

07842480

ABSTRACT:
The invention provides an immunogenic or antigenic polypeptide containing a translocation domain, a peptide epitope, at least one biologically active agent, and cleavage sites. These polypeptides are useful for activating T cell responses.

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Tang et al., 1999, “The Carboxyl Terminus of RNA Helicase A Contains a Bidirectional Nuclear Transport Domain”, Mol. Cell. Biol., 19(5):3540-3550.

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