Chimeric antibodies

Details Chimeric antibodies Chimeric antibodies

1989-04-09

1992-12-08

Nucker, Christine M.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

5303877, 5303915, 5303919, 435174, 435188, 435 697, 435194, 4353201, C07K 1528, C07K 1706

Patent

active

051699397

ABSTRACT:
Chimeric antibodies comprised of the variable region of an antibody chain contiguous with a polypeptide other than the constant region of that antibody chain are disclosed. Such chimeric antibodies can be comprised of the variable region of a chain of an immunoglobulin of selected specificity and an extrinsic polypeptide. In addition to the variable region of a chain of an immunoglobulin of selected specifity and an extrinsic polypeptide, the chimeric antibodies can include at least a portion of the constant region of an immunoglob

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