Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1991-12-11
1995-06-27
Hutzell, Paula
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
53038825, 43524027, 4351722, 435 7021, 4352402, C07K 1618, C12N 510, C12N 520
Patent
active
054281334
ABSTRACT:
Chimeric antibodies which bind to unique antigenic epitopes of IgE (designated ige.b1) which are present on IgE-bearing B lymphocytes but not basophils are described.
REFERENCES:
patent: 4714759 (1987-12-01), Whitaker
patent: 4940782 (1990-07-01), Rup et al.
patent: 5180805 (1992-01-01), Gould et al.
Morrison, Science 229:1202-1207, 1985.
Hochman et al., Biochemistry 12:1130-1135, 1973.
Qi et al. Biotechniques vol. 4:214 1986.
Baniyash, M. "Immunochemical Characterization of the Interaction Between Immunoglobulin E and its Receptor" PhD Thesis, Weizmann Int. of Science, Catalogued Aug. 12, 1990 pp. 84-85.
Hook et al. Mol. Immunol. 28:631-639, 1991.
Hook, W. A. et al. "Monoclonal Antibodies Defining Epitopes on IgE" FED Proc. 46:1346 (1987).
Hook, W. A. et al. "Histamine Release by Structural Analysis of LNRH" FED Proc. 44:1523 (1985).
Hook, W. A. et al. "Differential Binding of MABS to Fluid Phase vs. Basophil-Bound IgE" Clinical Research 33:515A (Apr. 1985).
Hook, W. A. et al. "Detection of Different Antigenic Sites on Human IgE Using Monoclonal Antibodies" Fed. Proc. 42:713 (1983).
Hook, W. A. et al. "Monoclonal Antibodies to Human IgE" Fed. Proc. 40:965 (1981).
Hook, W. A. et al. "Heterogeneity of Monoclonal Antibodies whicb Bind Unheated or Heated Human IgE" Fed. Proc. 41:825 (1982).
Banigish, M. "Relationships Between Epitopes on IgE Recognized by Defined mABS and by the Fc Receptor on Basophils" J. Immunol. 136:588-592 (1986).
Bangish, M. et al. "Inhibition of IgE binding to mast cells and basophils by monoclonal antibodies to murine RE" Eur. J. Immmol., 14:799-807 (1984).
DeConti Giulio A.
Hutzell Paula
Mirabel Eric P.
Tanox Biosystems, Inc.
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