Chimeric amino acid analogues

Details Chimeric amino acid analogues Chimeric amino acid analogues

1989-09-22

1992-06-09

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548558, 548566, C07D20704

Patent

active

051208598

ABSTRACT:
A chimeric amino acid analogue is provided suitable for incorporating into peptides which compound is represented by Formula 1: ##STR1## where P.sub.1 is preferably an amine protecting agent, and P.sub.2 and P.sub.3 are preferably amine or guanidine protecting agents. X can be OH, halide, or preferably an activating group suitable for conjugating the compound of Formula 1 to a peptide by conventional means, and m and n are 0-1 and 0-2 respectively.
Peptides containing the chimeric amino acid analog are provided and include a platelet-aggregation inhibitor represented by

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