Chimeric adenoviral vectors

Details Chimeric adenoviral vectors Chimeric adenoviral vectors

2011-02-01

2011-02-01

Wehbe, Anne Marie S (Department: 1633)

Chemistry: molecular biology and microbiology

Vector, per se

C514S04400A, C424S199100

Reexamination Certificate

active

07879602

ABSTRACT:
The present invention provides chimeric adenoviral vectors and methods for using the vectors to elicit an immune response to an antigen of interest.

REFERENCES:
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patent: 2005/0239728 (2005-10-01), Pachuk et al.
patent: 2007/0219149 (2007-09-01), Hasegawa et al.
patent: WO 2004/011624 (2004-02-01), None
patent: WO 2005/014038 (2005-02-01), None
Ichinohe et al. (2005) J. Virol. vol. 79, No. 5, 2910-2919.
Bell et al. (2006) PNAS, vol. 103(23), 8792-8797.
Alexopoulou, L., et al., “Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3,”Nature, vol. 413, pp. 732-738 (Oct. 18, 2001).
Ichinohe, T., et al., “Synthetic double-stranded RNA poly(I:C) Combined with mucosal vaccine protects against influenza virus infection,”Journal of Virology, vol. 79(5), pp. 2910-2919 (Mar. 2005).

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