Chemistry: molecular biology and microbiology – Vector – per se
Patent
1995-02-21
1998-06-23
Degen, Nancy
Chemistry: molecular biology and microbiology
Vector, per se
435 691, 435 697, 53038822, 536 242, C12N 1567, C12N 1586, C07H 2104, C12P 2102
Patent
active
057704422
ABSTRACT:
A recombinant adenovirus comprising a chimeric fiber protein and a therapeutic gene, a method of gene therapy involving the use of such an adenovirus, and an adenoviral transfer vector for the generation of such a recombinant adenovirus are provided.
REFERENCES:
patent: 4487829 (1984-12-01), Sharp et al.
patent: 4517686 (1985-05-01), Ruoslahti et al.
patent: 4578079 (1986-03-01), Ruoslahti et al.
patent: 4589881 (1986-05-01), Pierschbacher et al.
patent: 4593002 (1986-06-01), Dulbecco
patent: 4792525 (1988-12-01), Ruoslahti et al.
patent: 4797368 (1989-01-01), Carter et al.
patent: 4956281 (1990-09-01), Wallner et al.
patent: 5024939 (1991-06-01), Gorman
patent: 5096815 (1992-03-01), Ladner et al.
patent: 5166320 (1992-11-01), Wu et al.
patent: 5198346 (1993-03-01), Ladner et al.
patent: 5204445 (1993-04-01), Plow et al.
patent: 5223394 (1993-06-01), Wallner
patent: 5223409 (1993-06-01), Ladner et al.
patent: 5240846 (1993-08-01), Collins et al.
patent: 5246921 (1993-09-01), Reddy et al.
patent: 5332567 (1994-07-01), Goldenberg et al.
patent: 5349053 (1994-09-01), Landolfi
patent: 5403484 (1995-04-01), Ladner et al.
patent: 5436146 (1995-07-01), Shenk et al.
patent: 5443953 (1995-08-01), Hansen et al.
patent: 5474935 (1995-12-01), Chatterjee et al.
patent: 5521291 (1996-05-01), Curiel et al.
patent: 5534423 (1996-07-01), Palsson et al.
patent: 5543328 (1996-08-01), McClelland et al.
patent: 5547932 (1996-08-01), Curiel et al.
patent: 5552311 (1996-09-01), Sorscher et al.
patent: 5559099 (1996-09-01), Wickham et al.
patent: 5571698 (1996-11-01), Ladner et al.
patent: 5661133 (1997-08-01), Leiden et al.
patent: 5672344 (1997-09-01), Kelley et al.
patent: 5674722 (1997-10-01), Mulligan et al.
Batra et al., Gene Therapy, 1, 255-260 (1994).
Boursnell et al., Gene, 13, 311-317 (1981).
Caillet-Boudin et al., J. Mol. Biol., 217, 477-486 (1991).
Cotten et al., Proc. Natl. Acad. Sci., 87, 4033-4037 (1990).
Curiel et al., Proc. Natl. Acad. Sci., 88, 8850-8854 (1991).
Falgout et al., J. Virol., 62, 622-625 (1988).
Grubb et al., Nature, 371, 802-806 (1994).
Hong et al., Virology, 185, 758-767 (1991).
Karyan et al., Virology, 202, 782-785 (1994).
Mastrangeli et al., "in vivo Gene Transfer to the Lung of Experimental Animals using a chimeric Ad5/Ad7 Adenovirus vector," Ped. Pulm., Suppl. 12, 230, Ab. No. 180 (1995).
Mathias et al., J. Virol., 68, 6811-6814 (1994).
Michael et al., J. Biol. Chem., 268 6866-6869 (1993).
Michael et al., Gene Therapy, 2, 660-668 (1995).
Miller et al., FASEB J., 9, 190-199 (1995).
Nemerow et al., In Biology of Vitronectins and Their Receptors (Preissner et al., eds), 177-184 (Elsevior Science Publishers, 1993).
Nemerow et al., Trends in Cell Biology, 4, 52-55 (1994).
Wagner et al., Proc. Natl. Acad. Sci., 89, 6099-6103 (1992).
Wickham et al., J. Cell Biol, 127, 257-264 (1994).
Database WPI, Week 9017, Derwent Publications Ltd., AN 90-129060/17 (JP 2, 078, 631 abstract).
Bai et al., "Mutations That Alter an Arg-Gly-Asp (RGD) Sequence in the Adenovirus Type 2 Penton Base Protein Abolish Its Cell-Rounding Activity and Delay Virus Reproduction in Flat Cells," Journal of Virology, 67(9), 5198-5205 (1993).
Chroboczek et al., "The Sequence of the Genome of Adenovirus Type 5 and its Comparison with the Genome of Adenovirus Type 2," Virology, 186, 280-285 (1992).
Cotten et al., "High-Efficiency Receptor-Mediated delivery of Small and Large (48 Kilobase Gene Constructs Using the Endosome-Disruption Activity of Defective or Chemically Inactivated Adenovirus Particles," Proc. Natl. Acad. Sci. USA, 89, 6094-6098 (1992).
Curiel et al., "High-Efficiency Gene Transfer Mediated by Adenovirus Coupled to DNA-Polylysine Complexes," Human Gene Therapy, 3, 147-154 (1992).
Defer et al., "Human Adenovirus-Host Cell Interactions: Comparitive Study With Members of Subgroups B and C," Journal of Virology, 64(8), 3661-3673 (1990).
Green et al., "Evidence for a Repeating Cross-.beta. Sheet Structure in the Adenovirus Fibre," The EMBO Journal, 2(8), 1357-1365 (1983).
Henry et al., "Characterization of the Knob Domain of the Adenovirus Type 5 Fiber Protein Expressed in Escherichia coli," Journal of Virology, 68(8), 5239-5246 (1994).
Novelli et al., "Deletion Analysis of Functional Domains in Baculovrius-Expressed Adenovirus Type 2 Fiber," Virology, 185, 365-376 (1991).
Peteranderl et al., "Trimerizationm of the Heat Shock Transcription Factor by a Triple-Stranded .alpha.-Helical Coiled-Coil," Biochemistry, 12272-12276 (1992).
Signas et al., "Adenovruis 3 Fiber Polypeptide Gene: Implications for the Structure of the Fiber Protein," Journal of Virology, 53(2), 672-678 (1985).
Watson et al., "An Antigenic Analysis of the adenovirus Type 2 Fibre Polypeptide," Journal of Virology, 69, 525-535 (1988).
Wickham et al., "Integrins .alpha..sub.v .beta..sub.3 and .alpha..sub.v .beta..sub.5 Promote Adenovirus Internalization but Not Virus Attachment," Cell, 73, 309-319 (1993).
Abstract of grant application No. 1 P01 HL51746-01UB: 0004, "Gene Therapy For Cystic Fibrosis" Falck-Pedersen, submitted to the National Institutes of Health, (1994).
Albiges-Rizzo et al., Journal of Biological Chemistry, 266(6), 3961-3967 (1991).
Ball-Goodrich et al., Virology, 184, 175-186 (1991).
Chu et al., Gene Therapy, 1, 292-299 (1994).
Crystal, Science, 270, 404-410 (1995).
Dupuit et al., Human Gene Therapy, 6, 1185-1193 (1995).
Etienne-Julan et al., Journal of General Virology, 73, 3251-3255 (1992).
Greber et al., Cell, 75, 477-486 (1993).
Han et al., Proc. Natl. Acad. Sci. USA, 92, 9747-9751 (1995).
Horvath et al., Journal of Virology, (62) (1), 341-345 (1988).
Huang et al., Journal of Virology, 69 (4), 2257-2263 (1995).
Kass-Eisler et al., Proc. Natl. Acad. Sci. USA, 90, 11498-11502 (1993).
Komoriya et al., Journal of Biological Chemistry, 266(23), 15075-15079 (1999).
Maraveyas et al., Acta Onocologica, 32(7/8), 741-746 (1993).
Mastrangeli et al., Human Gene Therapy, 7, 79-87 (1996).
Michael et al., presented at Adenovirus Workshop: St. Andrews University, p. 52 (Jul. 13-15, 1995).
Neda et al., Journal of Biological Chemistry, 266(22), 14143-14146 (1991).
Russel et al., Nucleic Acids Research, 21(5), 1081-1085 (1993).
Silver et al., Virology, 165, 377-387 (1988).
Stewart et al., EMBO Journal, 12(7), 2589-2599 (1993).
Watkins et al., presented at Keystone Symposium on Molecular and Cellular Biology, Abst. No. 336.
Wickham et al., Gene Therapy, 2, 750-756 (1995).
Orkin et al., "Report and Recommendations of the Panel to Assess the NIH Investment in Research on Gene Therapy" Dec. 1995.
Bruder Joseph T.
Falck-Pedersen Erik
Gall Jason
Kovesdi Imre
Roelvink Petrus W.
Cornell Research Foundation Inc.
Degen Nancy
GenVec, Inc.
LandOfFree
Chimeric adenoviral fiber protein and methods of using same does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Chimeric adenoviral fiber protein and methods of using same, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chimeric adenoviral fiber protein and methods of using same will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1393726