Chicken infectious anemia virus vaccine

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant virus encoding one or more heterologous proteins...

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4241851, 4241861, 4241921, 4241931, 42419611, 4242021, 4242041, 4242141, 4242291, 4242781, 424816, 435 691, 435 693, 4352351, 4352523, 43525411, 4353201, 536 2372, A61K 3912, C12N 1534, C12N 701, C12N 510

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059651393

ABSTRACT:
Novel sequences in the genome of a wild type isolate of chicken infectious anemia virus are described, The amino acid sequence of a polypeptide, VP1, encoded by a novel sequence is also disclosed. Additionally, disclosed are the unexpected properties of the isolate which are related to novel amino acids positioned in the amino acid sequence of this isolate's VP1, as compared to the sequence of VP1 found in cell culture-adapted strains; and use of the novel sequences and their respective polypeptides in strategies to control chicken infectious anemia such as by vaccination.

REFERENCES:
patent: 5554525 (1996-09-01), Sondermaijer et al.
Claessens et al., "Molecular Cloning and sequence analysis of the genome of chicken anaemia agent", Journal of General Virology, 72, 1991, pp. 2003-2006.
Noteborn et al., "Characterization of Cloned Chicken Anemia Virus DNA That Contains All Elements for the Infectious Replication Cycle", Journal of General Virology, 72, 1991, pp. 2003-2006.
Meehan et al., "Characterization of viral DNAs from cells infected with chicken anaemia agent: sequence analysis of the cloned replicative form and transfection capabilities of cloned genome fragments", Archives of Virology, 124 (1992) pp. 301-319.

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