Chicken growth hormone releasing hormone receptor

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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Details

C530S350000, C530S399000

Reexamination Certificate

active

07078514

ABSTRACT:
The present invention relates to chicken growth hormone releasing hormone (GHRH), its corresponding receptor, and nucleic acid sequences encoding these proteins. More particularly the present invention is directed to the use of the chicken GHRH hormone and its corresponding GHRH receptor to enhance the production of larger, leaner chickens and other avian species used for meat production.

REFERENCES:
patent: 5973114 (1999-10-01), Thorner et al.
patent: WO 9832857 (1998-07-01), None
Porter et al., Ontogeny of growth hormone (GH)-secreting cells during chickent embryonic development: initial somatotrophs are responsive to GH-releasing hormone, Endocrinol. 136(5):1850-1856, 1995.
Hiroyuki Kaiya et al., “Chicken Ghrelin: Purification, cDNA Cloning, and Biological Activity,”Endocrinology143(9):3454-3463 (2002) The Endocrine Society, Great Britain.
E.R. Kuhn et al., “The Release of Growth Hormone (GH): Relation to the Thyrotropic- and Corticotropic Axis in the Chicken,”Domestic Animal Endocrinology, 29:43-51 (2005), Elsevier.
K. Peeters et al., “Effects of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) on cAMP Formation and Growth Hormone Release from Chicken Anterior Pituitary Cells,”Annals New York Academy of Sciences, 865:471-4 (1998).
M. Montero et al., “Molecular Evolution of the Growth Hormone-Releasing Hormone/Pituitary Adenylate Cyclase-Activating Polypeptide Gene Family. Functional Implication in the Regulation of Growth Hormone Secretion,”Journal of Molecular Endocrinology25:157-168 (2000), Society for Endocrinology, Great Britain.
S. Harvey, “Growth Hormone Secretion in Poikilotherms and Homeotherms,”The Endocrinology of Growth, Development, and Metabolism in Vertebratespp. 151-182. Eds PKT Pang, M Schriebman & CG Scanes (1993) Academic Press, New York.
A. O.L. Wong et al., Pituitary Adenylate Cyclase Activating Polypeptides as a Novel Hypophysiotropic Factor in Fish,Biochemistry and Cell Biology78(3):329-343 (2000), NRC Research Press, Canada.

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