Chicken growth differentiation factor-8

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C530S351000, C514S002600, C514S008100, C514S012200

Reexamination Certificate

active

07732571

ABSTRACT:
Chicken growth differentiation factor-8 (GDF-8) is disclosed along with fragments and pharmaceutical compositions thereof.

REFERENCES:
patent: 5585479 (1996-12-01), Hoke et al.
patent: 5616561 (1997-04-01), Barcellos-Hoff
patent: 5827733 (1998-10-01), Lee et al.
patent: 6468535 (2002-10-01), Lee et al.
patent: WO 91/08291 (1991-06-01), None
patent: WO 94/21681 (1994-09-01), None
patent: WO 98/33887 (1998-08-01), None
patent: WO 99/02667 (1999-01-01), None
patent: WO 99/40181 (1999-08-01), None
patent: WO 99/42573 (1999-08-01), None
Bowie et al., “Deciphering the Message in Protein Sequences: Tolerance to Amino Acid Substitutions”,Science, 247:1307-1310 (1990).
Bradley et al., “Modifying the Mouse: Design and Desire”,Biotechnology, vol. 10, pp. 534-539, May 1992.
Callard et al., “IL-1”,The Cytokine FactsBook, Academic Press, London, pp. 31-32 (1994).
Cameron, E.R., “Recent Advances in Transgenic Technology”,Molecular Biotechnology, 7(3):253-265 (1997).
Constam, D. B. and Robertson, E. J., “Regulation of Bone Morphogenetic Protein Activity by Pro Domains and Proprotein Convertases”,J. Cell. Biol., vol. 144, No. 1, pp. 139-149, 1999.
Deli et al., “Biochemical Study of Muscle Samples from Chicken Embryos Affected by Wofatox 50 EC”,Archives of Toxicology, vol. 8, pp. 277-279, see Abstract (1985).
Ebert et al., “A Moloney MLV-Rat Somatotropin Fusion Gene Produces Biologically Active Somatotropin in a Transgenic Pig”,Molecular Endocrinology, vol. 2, pp. 277-283 (1988).
Eimon & Harland, “Effects of heterodimerization and proteolytic processing on Derriére and Nodal activity: implications for mesoderm induction inXenopus”, Development, 129:3089-3103 (2002).
Evock et al., “Pituitary Porcine Growth Hormone (pGH) and a Recombinant pGH Analog Stimulate Pig Growth Performance in a Similar Manner”,Journal of Animal Science, vol. 66, No. 8, pp. 1928-1941, see Abstract (1988).
Faulkner et al., “Effect of Testosterone Propionate on Performance and Carcass Characteristics of Heifers and Cows”,Journal of Animal Science, vol. 67, No. 8, pp. 1907-1915, see Abstract (1989).
Flakoll et al., “Influence of Alpha-Ketoisocaproate on Lamb Growth, Feed, Conversion, and Carcass Composition”,Journal of Animal Science, vol. 69, No. 4, pp. 1461-1467, see Abstract (1991).
Gonzalez-Cadavid et al., “Organization of the human myostatin gene and expression in healthy men and HIV-infected men with muscle wasting”,Proc. Natl. Acad. Sci. USA., 95(25):14938-14943 (1998).
Gura, T., “Antisense Has Growing Pains”,Science, vol. 270, pp. 575-577, Oct. 27, 1995.
Hammer et al., Genetic Engineering of Mammalian Embryos,Journal of Animal Science, vol. 63, pp. 269-278 (1986).
Hawley et al., “Disruption of BMP signals in embryonicXenopusectoderm leads to direct neural induction”,Genes&Development, 9:2923-29-35 (1995).
Kappel et al., “Regulating gene expression in transgenic animals”,Current Opinion in Biotechnology, vol. 3, pp. 548-553 (1992).
Martignoni et al, “Cancer cachexia”,Molecular Cancer, 2(36):1-3 (2003).
Massague, J., “The TGF-.beta. Family of Growth and Differentiation Factors”,Cell, 49:437-38, 1987.
McDowell et al., “Effects of Exogenous Growth Hormone on Milk Production and Nutrient Uptake by Muscle and Mammary Tissues of Dairy Cows in Mid-Lactation”,Australian Journal of Biological Sciences, vol. 40, No. 3, pp. 295-306, see Abstract (1987).
McPherron et al., “Regulation of skeletal muscle mass in mice by a new TGF-.beta. superfamily member”,Nature, 387(6628):83-90 (1997).
Moreadith et al., “Gene targeting in embryonic stem cells: the new physiology and metabolism”,J. Mol. Med., vol. 75, pp. 208-216 (1997).
Mountain et al., “Engineering antibodies for therapy”,Biotechnol., Genet, Eng., vol. 10, pp. 1-142 (abstract), Rev. 1992.
Mullins et al., “Perspectives Series: Molecular Medicine in Genetically Engineered Animals”,Journal of Clinical Investigation, vol. 98, pp. S37-S40 (1996).
Ngo et al., “Computational Complexity, Protein Structure Prediction, and the Levinthal Paradox”,The Protein Folding Problem and Tertiary Structure Prediction, Mertz & Le Grand, Editors, Birkhäuser Boston, pp. 491-495 (1994).
Onuma et al., “Multiplenodal-Related Genes Act Coordinately inXenopusEmbryogenesis”,Developmental Biology, 241:94-105 (2002).
Rudinger, J., “Characteristics of the amino acids as components of peptide hormone sequence”,Peptide Hormones., Parsons J.A., Ed., University Park Press, Baltimore, London, Tokyo, pp. 1-7 (1976).
Seamark, R.F., “Progress and emerging problems in livestock transgenesis: a summary perspective”,Reproduction, Fertility and Development, 6(5):653-657 (1994).
Strojek & Wagner, “The Use of Transgenic Animal Techniques for Livestock Improvement”,Genetic Engineering: Principles and Methods, vol. 10, pp. 221-246 (1988).
Wall, R.J., “Transgenic Livestock: Progress and Prospects for the Future”,Theriogenology, vol. 45, pp. 57-68 (1996).
Wan et al., “Immune Induction by a Protein Antigen and by a Peptide Segment of the Protein”,Adv. Exp. Med. Biol., 185:175-191 (1985).
Wells, J.A., “Additivity of Mutational Effects in Proteins”,Biochemistry, 29(37):8509-17 (1990).
Williams & Wagner, “Transgenic animals in integrative biology: approaches and interpretations of outcome”,J. Appl. Physiol., 88:1119-1126 (2000).
Zhu et al., “Dominant negative myostatin produces hypertrophy without hyperplasia in muscle”,FEBS Letters, 474:71-75 (2000).
Zhu et al., “Survey of Major Histocompatibility Complex Class II Haplotypes in Four Turkey Lines Using Restriction Fragment Length Polymorphism Analysis with Nonradioactive DNA Detection”,Poultry Science, vol. 74, No. 7, pp. 1067-1073, see Abstract (1995).
Kambadur et al., “Mutations inmyostatin(GDF8) in Double-Muscled Belgian Blue and Piedmontese Cattle”,Genome Research, 7:910-915 (1997).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Chicken growth differentiation factor-8 does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Chicken growth differentiation factor-8, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chicken growth differentiation factor-8 will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4248899

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.