Chewable molded tablet containing medicinally active substances

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Food or edible as carrier for pharmaceutical

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424465, 514785, 514786, 514961, A61K 920

Patent

active

057532559

ABSTRACT:
There is provided a chewable medicinal tableting composition comprising as proportions of the total composition which will further comprise the medicinally active component, as first essential component: capric triglyceride: about 30 to about 95% by weight, and as second essential component: the medicinally active ingredient: up to 60% by weight. Where the medicinally active ingrdient is less than about 30% by weight the composition further comprises as third essential component, a member of the group consisting of glyceryl monostearate, a mixture of glyceryl monostearate and glyceryl monopalmitate, and a mixture comprising at least about 40-50% by weight of glyceryl monostearate, and glyceryl distearate: up to 10% by weight. There are also disclosed methods of making these compositions.

REFERENCES:
patent: 5037319 (1991-08-01), Gottwald et al.
Caplus AN 1976:140735 (Abstract of JP 50-157517).
Caplus AN 1983:410812 (Abstract of Rogaska-Mascher et al., Farm. Pol. (1983) 39(1), 25-8.

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