Chewable drug-delivery compositions and methods for preparing th

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Matrices

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424485, 424440, A61K 914

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active

053805356

ABSTRACT:
A non-aqueous, chewable composition for oral delivery of unpalatable drugs is provided along with preparative methods therefor. The composition contains the drug intimately dispersed or dissolved in a pharmaceutically-acceptable lipid that is solid at room temperatures. The composition also has a matrix that contains a granulating agent for the total composition and a rapid dispersal agent and optionally additives such as buffering agents, flavoring agents, surfactants, and the like.

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