Chemotherapeutic agent and tracer composition and use thereof

Details Chemotherapeutic agent and tracer composition and use thereof Chemotherapeutic agent and tracer composition and use thereof

1982-05-12

1985-07-09

Warden, Robert J.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

424129, 436 63, 436172, 436800, 436805, 436811, 436815, 128653, 128659, 128760, 210645, 210646, 210647, 210648, 210651, 2103213, 210927, G01N 3348, G01N 3100, A61K 3300

Patent

active

045281785

ABSTRACT:
A therapeutic composition suitable for extracorporeal treatment of whole blood comprises a dialyzable chemotherapeutic agent and a dialyzable fluorescable tracer means. The removal rate of the fluorescable tracer compound from treated blood during hemodialysis is a function of the removal rate of unreacted chemotherapeutic agent present. The residual chemotherapeutic agent concentration after hemodialysis is ascertained by measuring the concentration of the fluorescable tracer compound in a dialysate using fluorometric techniques.

REFERENCES:
patent: 4017614 (1977-04-01), Wild
Babb, Report Carbamylated Red Cell Distributions in Blood Treated Extracorporeally with Cyanate, Nat. Heart, Lung & Blood Inst., Bethesda MD, Contract NO1-HB-6-2962, Jul. 1977.

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