Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.
Patent
1995-06-06
2000-02-29
Achutamurthy, Ponnathapura
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Lymphokines, e.g., interferons, interlukins, etc.
530350, 530324, 530325, C07K 1452
Patent
active
060310804
ABSTRACT:
A chemoattractant protein called "eotaxin" is capable of attracting eosinophils and of inducing eosinophil accumulation and/or activation in vitro and in vivo. Various types of agents that inhibit or otherwise hinder the production, release or activity of eotaxin may be used therapeutically in the treatment of asthma and other inflammatory diseases.
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Dahinden et al, "Monocyte Chemotactic Protein 3 Is a Most Effective Basophil-and Eosinophil-activating Chemokine", J. Exp. Med. 179:751-756 (1994).
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Griffiths-Johnson David A.
Hsuan John J.
Jose Peter J.
Williams Timothy J.
Achutamurthy Ponnathapura
Ludwig Institute for Cancer Research Imperial College of Science
Wessendorf T. D.
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