Chemosensitivity determination using phosphatidylserine

Details Chemosensitivity determination using phosphatidylserine Chemosensitivity determination using phosphatidylserine

2005-09-27

2005-09-27

Saucier, Sandra E. (Department: 1651)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

C435S007210

Reexamination Certificate

active

06949350

ABSTRACT:
A method for determining the chemosensitivity of cells towards at least one substance by measuring the apoptosis induced by said at least one substance, wherein the cells are incubated essentially concurrently with at least one marker whose interaction with phosphatidylserine can be detected and with said at least one substance, and the interaction between the marker and phosphatidylserine is detected in a time-resolved manner.

REFERENCES:
Scutte et al., “Annexin V binding assay as a tool to measure apoptosis in differentiated neuronal cells” J. Neuroscience Method 86 (1) : 63-69 (1998).
Han Chong Toh et al., “Vinorelbine Induces Apoptosis and Caspase-3 (Cpp32) Expression in Leukemia and Lymphoma Cells: a Comparison with Vincristine”,Leukemia and Lymphoma, 31, 195-208 (1998).
Vladimir D. Kravtsov et al., “Use of the Microculture Kinetic Assay of Apoptosis to Determine Chemosensitivities of Leukemmias”,Blood, 92, 968-980 (1998).
Antonius W.M. Boersma et al., “Bax Upregulation is an Early Event in Cisplatin-Induced Apoptosis in Human Testicular Germ-cell Tumor Cell Line Nt2, as Quantitated by Flow Cytometry”,Cytometry, 27, 275-282 (1997).

Affiliated with

Also associated with

Rating

Chemosensitivity determination using phosphatidylserine does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Chemosensitivity determination using phosphatidylserine, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chemosensitivity determination using phosphatidylserine will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3450535