Chemoselective fluorgenic molecular linkers and methods for...

Details Chemoselective fluorgenic molecular linkers and methods for... Chemoselective fluorgenic molecular linkers and methods for...

2005-04-15

2010-06-29

Haq, Shafiqul (Department: 1641)

Chemistry: analytical and immunological testing

Involving producing or treating antigen or hapten

Producing labeled antigens

C436S056000, C436S800000, C530S402000, C549S200000, C552S008000

Reexamination Certificate

active

07745229

ABSTRACT:
The present invention describes a bioconjugation strategy and compounds that are useful therein in which a fluorescent signal is produced when two molecular or supramolecular entities are linked by chemoselective combination of one linker having an azido or halide substituent group with another linker having a cyano or an alkyne substituent group. A kit is also provided.

REFERENCES:
patent: 3839351 (1974-10-01), Dorlars et al.
patent: 7365178 (2008-04-01), Campbell et al.
patent: 2005/0032081 (2005-02-01), Ju et al.
Saxon, E., et al.,Science, 287: 2007-10 (2000).
Breinbauer, R. et al.,Chembiochem, 4:1147-9 (2003).
Gaietta et al.,Science, 296:503-507 (2002).
Lemieux et al.,J. Am. Chem. Soc., 125:4708-4709 (2003).
Rostovtsev et al., Angew. Chem., Int. Ed., 41:2596-2599 (2002).
Tornoe et al., J. Org. Chem., 67:3057-3062 (2002).
Wang et al., J. Am. Chem. Soc., 125:3192-3193 (2003).
Speers et al., J. Am. Chem. Soc., 125:4684-4687 (2003).
Seo et al., J. Org. Chem., 68:609-612 (2003).
Lee et al., J. Am. Chem. Soc., 125:9588-9589 (2003).
Link et al., J. Am. Chem. Soc., 125:11164-11165 (2003).
Deiters et al., J. Am. Chem. Soc., 125:11782-11783 (2003).

Affiliated with

Also associated with

Rating

Chemoselective fluorgenic molecular linkers and methods for... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Chemoselective fluorgenic molecular linkers and methods for..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chemoselective fluorgenic molecular linkers and methods for... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4249070