Chemokine mimetics synthesis and their use

Details Chemokine mimetics synthesis and their use Chemokine mimetics synthesis and their use

2011-08-09

2011-08-09

Audet, Maury (Department: 1654)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C424S085200, C424S009100, C424S085100, C424S093700, C435S004000, C435S007100, C435S007930, C435S325000, C435S355000, C435S372000, C435S455000, C530S300000, C530S351000, C514S04400A

Reexamination Certificate

active

07994114

ABSTRACT:
The present disclosure generally teaches compositions comprising SDF-1 mimetics and methods of using them to modulate an activity of a cell having an SDF-1 receptor by binding the SDF-1 receptor to an SDF-1 mimetic. The cell can be a hematopoietic cell, for example, and can be selected from a group consisting of hematopoietic stem cells, hematopoietic progenitor cells, primitive granulocytes, primitive erythroid cells, leukocytes, and neutrophils. In some embodiments, the activity can include the rate of multiplication of the cell or, where the cell is a quiescent cell, the binding can repress the activation of the quiescent cell. Other embodiments of the present invention are taught herein.

REFERENCES:
patent: 2530369 (1950-11-01), Simons
patent: 2760992 (1956-08-01), Schoeffel et al.
patent: 4554101 (1985-11-01), Hopp
patent: 4868116 (1989-09-01), Morgan et al.
patent: 4980286 (1990-12-01), Morgan et al.
patent: 5082670 (1992-01-01), Gage et al.
patent: 5166320 (1992-11-01), Wu et al.
patent: 5399346 (1995-03-01), Anderson et al.
patent: 5401651 (1995-03-01), Walz
patent: 5563048 (1996-10-01), Honjo et al.
patent: 5756084 (1998-05-01), Honjo et al.
patent: 5807744 (1998-09-01), Berneman et al.
patent: 5856301 (1999-01-01), Craig et al.
patent: 5871723 (1999-02-01), Strieter et al.
patent: 5919776 (1999-07-01), Hagmann et al.
patent: 5962462 (1999-10-01), Mills et al.
patent: 5990163 (1999-11-01), Evans et al.
patent: 6013644 (2000-01-01), Mills et al.
patent: 6022848 (2000-02-01), Kozlov et al.
patent: 6046185 (2000-04-01), Burgoyne et al.
patent: 6124319 (2000-09-01), MacCoss et al.
patent: 6132987 (2000-10-01), Charo et al.
patent: 6133319 (2000-10-01), Widdowson
patent: 6136827 (2000-10-01), Caldwell et al.
patent: 6140349 (2000-10-01), Caldwell et al.
patent: 6166037 (2000-12-01), Budhu et al.
patent: 6204294 (2001-03-01), Bryan et al.
patent: 6356887 (2002-03-01), Berenson et al.
patent: 6515001 (2003-02-01), Saxena et al.
patent: 6613742 (2003-09-01), Huang et al.
patent: 6676937 (2004-01-01), Isner et al.
patent: 6693134 (2004-02-01), Saxena et al.
patent: 2002/0156034 (2002-10-01), Tudan et al.
patent: 2002/0165123 (2002-11-01), Tudan et al.
patent: 2003/0004136 (2003-01-01), Saxena et al.
patent: 2003/0045550 (2003-03-01), Saxena et al.
patent: 2003/0092674 (2003-05-01), Saxena et al.
patent: 2003/0125380 (2003-07-01), Saxena et al.
patent: 2003/0148940 (2003-08-01), Tudan et al.
patent: WO 89/02468 (1989-03-01), None
patent: WO 89/05345 (1989-06-01), None
patent: WO 89/07136 (1989-08-01), None
patent: WO 90/06757 (1990-06-01), None
patent: WO91/04274 (1991-04-01), None
patent: WO 92/07573 (1992-05-01), None
patent: WO 93/10234 (1993-05-01), None
patent: WO93/13206 (1993-07-01), None
patent: WO 95/05452 (1995-02-01), None
patent: WO 95/09236 (1995-04-01), None
patent: WO 96/40772 (1996-12-01), None
patent: WO 97/28257 (1997-08-01), None
patent: WO 97/28258 (1997-08-01), None
patent: WO 98/04684 (1998-02-01), None
patent: WO 98/04698 (1998-02-01), None
patent: WO 98/09642 (1998-03-01), None
patent: WO 98/51705 (1998-11-01), None
patent: WO 99/47158 (1999-09-01), None
patent: WO 0009152 (2000-02-01), None
patent: WO 01/76615 (2001-10-01), None
patent: WO 01/85196 (2001-11-01), None
patent: WO2004/024088 (2004-03-01), None
U.S. Appl. No. 10/243,795, filed Sep. 13, 2002, Merzouk, et al.
U.S. Appl. No. 10/932,208, filed Aug. 31, 2004, Merzouk, et al.
Acsadi, G., et al.,Nature 352:815-818, (1991).
Aiuti, A., et al.,J. Exp. Med.185(1):111-120, (1997).
Aiuti, A., et al.,Eur. J. Immunol. 29:1823-1831, (1999).
Alkhatib, G. et al.,Science 272:1955-1958, (1996).
Allen, M. et al.,J. Biomolecular Screening 5(2):63-69, (2000).
Alleva, D., et al.,J. Immunol. 161(12):6878-6884, (1998).
Anderlini, P., et al.,Blood 90(3), 903-908, (1997).
Anderson, W., et al.,Science 288:627-629, (2000).
Arenzana-Selsdedos, F., et al.,Nature 383:400, (1996).
Armentano, D., et al.,Proc. Nat'l. Acad. Sci. 87:6141-6145, (1990).
Ausubel, et al.,Current Protocols in Mol. Biol. Supp. 36:9.10.1-9.14.6, (1995).
Avenarius, H., et al.,Inter. J. Hematology 58:189-196, (1993).
Baggiolini, M.,Nature 392:565-568, (1998).
Baird, A., et al.,Current Opinion in Immunology 11:157-166, (1999).
Balasa, B., et al.,J. Exp. Med. 186:385-391, (1997).
Baldari, et al.,The EMBO J. 6(1):229-234, (1987).
Barbier, J., et al.,J. Med. Chem. 40(9):1373-1380, (1997).
Barbier, J., et al.,Biochemistry 39(47)14522-14530, (2000).
Barnerji, et al.,Cell 33:729-740, (1983).
Barnes, D., et al.,J. Clin. Invest. 101(12):2910-2919, (1998).
Batory, D., et al.,ACM transactions on Software Engineering and Methodology 1(4):355-398, (1992).
Belperio, et al.,J. Leukoc. Biol. 68:1-8, (2000).
Benoist, et al.,Nature 290:304-310, (1981).
Berkner, K.,Biotechinques 6(7):616-628, (1988).
van Beuschem, V., et al.,Proc. Nat'l. Acad. Sci 89:7640-7644, (1992).
Blease, K., et al.,J. Immunol. 165:1564-1572, (2000).
Bleul, C., et al.,J. Exp. Med. 184:1101-1109, (1996).
Bleul, C., et al.,Nature 382:829-832, (1996).
Bollon, et al.,J. of Clinical Hemotology and Oncology 10:39-48, (1980).
Bork, et al.,Trends in Genetics 12(10):425-427, (1996).
Bork, A.,Genome Res. 10:398-400, (2000).
Botstein, et al., “Making Mutations in Vitro and Putting them Back Into Yeast”, Dept of Biol. Massachussetts Institute of Technology, 265-274, (1982).
Brandt, J., et al.,J. Clin Invest. 86:932-941, (1990).
Brandt, J., et al.,Blood 79(3):634-641, (1992).
Brandt, J., et al.,J. Clin. Invest. 82:1017-1027, (1998).
Brenner, S.E.,Trends in Genetics 15(4):132-133, (1999).
Broach, J.R.,The Molecular Biology of the Yeast Saccharomyces, 445-470, (1981).
Broach, J.R.,Cell 28:203-204, (1982).
Buckley, C., et al.,J. lmmunol. 165:3423-3429, (2000).
Burt, R.,Stem Cells 17(6):366-372, (1999).
Buser, et al.,Methods in Molecular Biology 138:143-148, (2000).
Calame, et al.,Advances in Immunology 43:236-275, (1988).
Campbell, J., et al.,Science 279:381-383, (1998).
Camper, et al.,Genes&Development 3, 537-546, (1999).
Carr, M., et al.,Proc. Nat'l. Acad. Sci. 91:3652-3656, (1994).
Cashman, J., et al.,Blood 94(11):3722-3729, (1999).
Cavazzana-Calvo, M., et al.,Science288:669-672, (2000).
Cenatiempo, Y.,Biochimie 68:505-515, (1986).
Charo, I., et al.,Proc. Natl. Acad. Sci. 91:2752-2756, (1994).
Choe, H., et al.,Cell 85:1135-1148, (1996).
Chowdury, J., et al.,Science 254:1802-1805, (1991).
Clapp, W., et al.,Blood 78(4):1132-1139, (1991).
Clark-Lewis, I., et al.,J. Biol. Chem. 269(23):16075-16081, (1994).
Cocchi, F., et al.,Science 270:1811-1815, (1995).
Colosimo, et al.,BioTechniques 29:314-331, (2000).
Combadiere, C., et al.,J. Biol. Chem. 270:16491-16494, (1995).
Conti, J., et al.,Cancer 70(11):2699-2702, (1992).
Cristiano, R., et al.,Proc. Nat'l. Acad. Sci. 90:2122-2126, (1993).
Crump, M., et al.,EMBO Journal 16(23):6996-7007, (1997).
Curiel, D., et al.,Proc. Nat'l. Acad. Sci. 88:8850-8854, (1991).
Cushing, S., et al.,Proc. Nat'l. Acad. Sci. 87:5134-5138, (1990).
Cwirla, S., et al.,Science 276:1696-1699, (1997).
Dai, Y., et al.,Proc. Nat'l. Acad. Sci. 89:10892-10895, (1992).
Danos, O., et al.,Proc, Nat'l. Acad. Sci. 85:6460-6464, (1988).
Daugherty, et al.,Chemokine Protocols 138:129-148, (2000).
Daugherty, et al.,Methods in Molecular Biology 138:129-134, (2000).
Demirer, T., et al.,Stem Cells 14:106-116, (1996).
DeNardo, et al.,Cancer 94:1275-1286, (2002).
Deng, H., et al.,Nature 381:661-666, (1996).
Dhib-Jalbut, S., et al.,Journal of Interferon and Cytokine Research 16:195-200, (1996).
Di Salvo, J., et al.,Eur. J. Pharm. 409:143-154, (2000).
Doerks, et al.,Trends in Genetics 14(6):248-250, (1998).
Doranz, B., et al.,Cell 85:1149-1158, (1996).
Dragic, T., et al.,Nature 381:667-673, (1996).
Dufour, J.H., et al.,The Journal of Immunology 167(7077-7083):3195-3204, (2001).
Dunican, A., et al.,Shock 13(3):244-250, (2000).
Durig, J., et al.,Leukemia 14:1652-1660, (2000).
Edlund, et al.,Science 28:912-916, (1985).
Eglitis, M., et al.,Science 320:1395-1398, (1985).
Elisseeva, E., et al.,J. Biol. Chem. 275(35):26799-26805, (2000).
Elseviers, M. et al.,Biochem. and Biophys. Research Comm. 154(2)515-521

Affiliated with

Also associated with

Rating

Chemokine mimetics synthesis and their use does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Chemokine mimetics synthesis and their use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chemokine mimetics synthesis and their use will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2711776