Chemokine expressed in eosinophils

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 221, 536 243, 536 2431, 536 2433, 536 245, 435 691, C07H 2102, C07H 2104, C12P 2100

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060516976

ABSTRACT:
The present invention provides nucleotide and amino acid sequences that identify and encode a novel chemokine (EEC) expressed in human eosinophil cells. The present invention also provides for antisense molecules to the nucleotide sequences which encode EEC, expression vectors for the production of purified EEC, antibodies capable of binding specifically to EEC, hybridization probes or oligonucleotides for the detection of EEC-encoding nucleotide sequences, genetically engineered host cells for the expression of EEC, diagnostic tests for chemokine activation based on EEC-encoding nucleic acid molecules and antibodies capable of binding specifically to the protein.

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Kwon, et al., "A new chemokine, MMRP2", GenBank Accession No. U15209, Sep. 1994.

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