Compositions – Chemiluminescent
Patent
1997-05-13
1998-06-30
Tucker, Philip
Compositions
Chemiluminescent
435 4, C09K 300, C12Q 100
Patent
active
057729263
ABSTRACT:
Novel methods and compositions which generate chemiluminescence are provided. The compositions comprise a heterocyclic enol phosphate compound and a dihydroxyaromatic compound in which the two hydroxy groups are separated by an even number of ring carbon atoms.
Novel methods and compositions for generating chemiluminescence by reaction with a hydrolytic enzyme are provided as well. The compositions comprise a heterocyclic enol phosphate compound and a protected dihydroxyaromatic compound in which one of the hydroxy groups of the dihydroxyaromatic compound is protected with an enzyme-cleavable group.
The novel chemiluminescent compositions are useful in methods for producing chemiluminescence for use in assays of hydrolytic enzymes and enzyme inhibitors and in assays employing labeled specific binding pairs.
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Handley Richard S.
Lumigen Inc.
Tucker Philip
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