Chemiluminescent phenanthridinium

Details Chemiluminescent phenanthridinium Chemiluminescent phenanthridinium

1995-05-16

1997-09-23

Spiegel, Carol A.

Chemistry: analytical and immunological testing

Biospecific ligand binding assay

435 6, 435 71, 435968, 436518, 436536, 436544, 436546, 436548, 436800, 5303898, 536 271, 546104, G01N 3100

Patent

active

056698194

ABSTRACT:
Acridinium sulfonylamides and isomers, such as phenanthridinium sulfonylamides, may be employed in applications including chemiluminmescent immunoassays. Methods for synthesis of these compounds include contacting an amine with a sulfonylhalide to form a sulfonamide and acylating with an activated carboxylic acid of an acridine or isomer thereof. The N-sulfonyl-9-acridinium carboxamide and isomers may be conjugated to antigens, haptens, antibodies, and nucleic acids for use in chemiluminescent assays.

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