Chemiluminescent naphthalene-1,2-dicarboxylic acid hydrazide-lab

Details Chemiluminescent naphthalene-1,2-dicarboxylic acid hydrazide-lab Chemiluminescent naphthalene-1,2-dicarboxylic acid hydrazide-lab

1978-07-24

1980-09-30

Schain, Howard E.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

23230B, 260112R, 2601125R, 2601127, 424 8, 424 12, 424 85, 424 88, 435 7, 435188, 525420, C07G 700

Patent

active

042254850

ABSTRACT:
Chemiluminescent-labeled conjugates of the formula: ##STR1## wherein R is hydrogen or straight chain alkyl containing 1-4 carbon atoms, n=2-6 and L(CO-- is a specifically bindable ligand, such as an antigenic protein or polypeptide, a hapten or an antibody, or a binding analog thereof, bound through an amide bond; and intermediates produced in the synthesis of such conjugates. The labeled conjugates are useful as reagents in specific binding assays for determining ligands or their specific binding partners in liquid media.

REFERENCES:
patent: 3875011 (1975-04-01), Rubenstein et al.
patent: 4011219 (1977-03-01), Nishii et al.
patent: 4058511 (1977-11-01), Singh
patent: 4065354 (1977-12-01), Ullman et al.
patent: 4069105 (1978-01-01), Singh
patent: 4104029 (1978-08-01), Maier, Jr.
Dictionary of Biochemistry, Stenesh, 1977, pp. 21 and 135.
Condensed Chemical Dictionary, 8th Ed., Hawley, 1976, pp. 42, 711 and 737.
Journal of Immunological Methods, 21-179-184 (1978), Pratt et al.

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