Chemistry: analytical and immunological testing – Involving producing or treating antigen or hapten – Producing labeled antigens
Patent
1989-11-30
1990-12-04
Nucker, Christine
Chemistry: analytical and immunological testing
Involving producing or treating antigen or hapten
Producing labeled antigens
436536, 436800, 548513, 549332, C07D20938, C07D20946, C07D30300, G01N 33533
Patent
active
049753800
ABSTRACT:
Thermochemically induced luminescence is generated in a fluorescent labeled organic compound containing a covalently bonded fluorescent label which is a polycyclic aromatic radical having at least three linearly fused benzene rings and capable of being excited to a fluorescent electronic excited state by energy transfer from an energy donor molecule or radical having an electronic excited state, by a process comprising generating an energy donor radical or molecule by a thermochemical reaction in the presence of the fluorescent label. The energy donor radical may be generated by a chemical reaction in the presence of the fluorescent labeled organic compound or the fluorescent labeled compound itself may be additionally labeled with a radical capable of being excited to an electronic excited state by a thermochemical reaction, i.e., by a process initiated by adsorption of thermal energy.
Hummelen Jan C.
Wynberg Hans
Blackstone William M.
Krupen Karen I.
Nucker Christine
Rijksuniversiteit te Groningen
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