Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving oxidoreductase
Patent
1995-06-07
1997-05-13
Kight, John
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving oxidoreductase
435 25, 435 27, 435 24, 435 794, 435 793, 435810, 435975, 435 4, 436501, 436546, 436808, 436 63, 558287, 558286, C12Q 128, C12Q 126, C12Q 100, G01N 33566
Patent
active
056291680
ABSTRACT:
Method of increasing the light output and/or signal:background ratio of light output from a chemiluminescent reaction of a dihydrophthalazinedione, a peroxidase enzyme catalyst and an oxidant, by carrying out the reaction in the presence of an enhancer which is an aromatic organo boron compound. Kits suitable for use in diagnositc assays comprising such enhancers are also described.
REFERENCES:
patent: 4868130 (1989-09-01), Hargreaves
patent: 4950613 (1990-08-01), Arnold, Jr. et al.
Burnett et al, Biochemical & Biophysical Research Comm, vol. 96, No. 1, pp. 157-162, (1980).
G.H. Thorpe and L.J. Kricka, "Enhanced Chemiluminescent Reactions Catalyzed by Horseradish Peroxidase", Methods in Enzymology 133, 331-353 (1986).
R.A. Bowie and O.C. Musgrave, "Organoboron compounds. Part VII . . . ", J. Chem Soc. (C), 485-488 (1970).
"Chemiluminescence Principles and Applications in Biology and Medicine" by A.K. Campbell, Ellis Horwood Ltd., 1988, pp. 81 and 82.
"Clinical and Biochemical Luminescence," Ed. L.J. Kricka and T.J.N. Carter, Marcel Decker, 1982, pp.1 and 2.
"Advanced Organic Chemistry" by Jerry March, 4th ed., 1992 at pp. 231-238.
British Technology Group Limited
Kight John
Leary Louise N.
LandOfFree
Chemiluminescent enhancers does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Chemiluminescent enhancers, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chemiluminescent enhancers will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1384437