Chemiluminescent electron-rich aryl-substituted 1,2-dioxetanes

Details Chemiluminescent electron-rich aryl-substituted 1,2-dioxetanes Chemiluminescent electron-rich aryl-substituted 1,2-dioxetanes

1995-05-09

1997-03-04

Tucker, Philip

Compositions

Chemiluminescent

435 4, 435 5, 435 6, 422 52, C09K 300, G01N 2176

Patent

active

056076258

ABSTRACT:
Chemiluminescent electron-rich aryl-substituted 1,2-dioxetane compounds are disclosed in which the aryl group is poly-substituted with suitable electron-donating groups such that the light-emitting pattern of the molecule results in a very high luminescent count, thus providing for a sensitive and precise assay for haptens, analytes, polynucleotides and the like. These substituted aryl-containing 1,2-dioxetane compounds can be used as direct labels in an immunoassay or when derivatized with an appropriate leaving group, can be used as a substrate for a enzyme immunoassay. The unusual chemiluminescence of the compounds allows the timing of the luminescent reaction to be exactly controlled.

REFERENCES:
patent: 4931223 (1990-06-01), Bronstein et al.
patent: 4931569 (1990-06-01), Edwards et al.
patent: 4952707 (1990-08-01), Edwards et al.
patent: 5112960 (1992-05-01), Bronstein et al.

Affiliated with

Also associated with

Rating

Chemiluminescent electron-rich aryl-substituted 1,2-dioxetanes does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Chemiluminescent electron-rich aryl-substituted 1,2-dioxetanes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chemiluminescent electron-rich aryl-substituted 1,2-dioxetanes will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2144004