Compositions – Chemiluminescent
Patent
1994-11-23
1996-11-26
Tucker, Philip
Compositions
Chemiluminescent
435 4, C09K 300
Patent
active
055782531
ABSTRACT:
A chemiluminescent assay method and compositions are described which use a dialkyl-substituted dioxetane which is deprotected to trigger a chemiluminescent reaction. Chemiluminescent 1,2-dioxetane compounds substituted on the dioxetane ring with two nonspirofused alkyl groups which can be triggered by a reagent to generate light are disclosed. Dialkyl-substituted dioxetanes are useful for the detection of triggering agents including enzymes. The enzyme may be present alone or linked to a member of a specific binding pair in an immunoassay, DNA probe assay or other assay where the enzyme is bound to a reporter molecule.
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Akhavan-Tafti Hashem
Schaap Arthur P.
Lumigen Inc.
McLeod Ian C.
Tucker Philip
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