Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving oxidoreductase
Patent
1999-06-25
2000-07-11
Leary, Louise N.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving oxidoreductase
435 4, 436 66, C12Q 128, C12Q 100
Patent
active
060871210
ABSTRACT:
Assays are disclosed for evaluating the presence or amount of a heme protein in a sample. The assays are based on chemiluminescence. Assay solutions include the sample, a suitable substrate and an oxidizing agent. The substrate is selected to undergo a specific reaction with the proteins of interest to produce an intermediate that emits light. suitable heme proteins include hemoglobin and myeloperoxidase. Suitable substrates include cyclic hydrazides and acridan derivatives.
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Bush Valerie
Hallaway Brenda J.
O'Kane Dennis J.
Ogbonna Godwin
Wilson David M.
Leary Louise N.
Mayo Foundation for Medical Education and Research
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