Chemiluminescent acridinium salts

Details Chemiluminescent acridinium salts Chemiluminescent acridinium salts

1995-01-03

1995-11-21

Spiegel, Carol A.

Chemistry: analytical and immunological testing

Biospecific ligand binding assay

435 6, 435 71, 435968, 436518, 436536, 436544, 436546, 436548, 436800, 436805, 5303898, 546104, G01N 3100

Patent

active

054686466

ABSTRACT:
Acridinium sulfonylamides and isomers, such as phenanthridinium sulfonylamides, may be employed in applications including chemiluminmescent immunoassays. Methods for synthesis of these compounds include contacting an amine with a sulfonylhalide to form a sulfonamide and acylating with an activated carboxylic acid of an acridine or isomer thereof. The N-sulfonyl-9-acridinium carboxamide and isomers may be conjugated to antigens, haptens, antibodies, and nucleic acids for use in chemiluminescent assays.

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