Chemiluminescence-based static and flow cytometry

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent

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424 2, 424 3, 424 71, 435 6, 435 4, 435 721, 435 724, G01N 3100, G01N 3348, G01N 3315, G01N 3353

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050323814

ABSTRACT:
Apparati and methods of use for static and flow cytometry of cells and other particulate matter that eliminate the need for a laser or other external energy source to separate and/or detect differences in cells and other particulate matter wherein components of cells and other particulate matter interact with added thermally, chemically, electrochemically, photochemically or enzymatically decomposible chemiluminescent compounds, to produce light energy emissions optically detectable by said apparati.

REFERENCES:
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patent: 4665020 (1987-05-01), Saunders
Herzenberg, L. A., et al., Sci. Amer. 234:108 (1976).
Kaplow, L. S., et al., J. Histochem. Cytochem. 25:590 (1977).
"Practical Flow Cytometry", Howard Shapiro, A. R. Liss, Inc., N.Y., 1985, pp. 9-276.
Truneh, A., et al., Cytometry 8:562 (1987).
Smith, R. E., et al., J. Histochem. Cytochem. 27:1499 (1979).
Dive, C., et al., Cytometry 8:552 (1987).
Goolsby, C., et al. Cytometry 9:126 (1988).

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