Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving viable micro-organism
Patent
1997-08-19
1999-01-26
Leary, Louise N.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving viable micro-organism
435 4, 435 29, 435 6, 436 94, 436800, 536 111, 536 2673, 536 256, C12Q 104, C12Q 100, C12Q 102
Patent
active
058637532
ABSTRACT:
The invention comprises cyanine dyes, in particular chemically reactive dyes, conjugates of reactive cyanine dyes, the non-covalent complexes of nucleic acids with the dyes and dye-conjugates of the invention, and a method of forming a nucleic acid complex with the dyes and dye-conjugates of the present invention. The dyes of the invention are useful for the preparation of dye-conjugates. The presence of a reactive group on the unsymmetrical cyanine dyes of the invention facilitates their covalent conjugation to a variety of substances, both biological and synthetic.
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Haugland Richard P.
Millard Paul J.
Singer Victoria L.
Yue Stephen T.
Helfenstein Allegra J.
Leary Louise N.
Molecular Probes, Inc.
Skaugset Anton E.
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