Chemically modified TNF-α

Drug – bio-affecting and body treating compositions – Lymphokine

Reexamination Certificate

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Details

C514S002600, C514S008100, C514S012200, C530S350000

Reexamination Certificate

active

06878370

ABSTRACT:
The present invention concerns a chemically modified TNF-α, and a pharmaceutical composition and a vaccine composition containing the chemically modified TNF-α which are useful for combating overproduction of native TNF-α.

REFERENCES:
patent: 4414147 (1983-11-01), Klibanov et al.
patent: 2 677 654 (1991-06-01), None
patent: 2 773 156 (1997-12-01), None
patent: WO 9421288 (1994-09-01), None
patent: WO 9421288 (1994-09-01), None
Tsunoda et al. (Mar. 1998), 56(3), pp. 573-578, Japanese Journal of clinical medicine.

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