Chemically defined vaccine against urinary infections

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

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530300, 530324, 530806, 530820, 530825, 424 88, 424 92, 514 2, 514 12, C07K 1300, C07K 1504, A61K 3908

Patent

active

047360178

ABSTRACT:
A vaccine effective in protecting mammals against urinary infections is prepared from purified Gal-Gal pilus proteins or fragments thereof.

REFERENCES:
patent: 4554101 (1985-11-01), Hopp
patent: 4606919 (1986-08-01), Stojkovic et al.
Wilson et al, "The Structure of an Antigenics Determinant in a Protein" Cell, vol. 37, 1984, pp. 767-768.
Nunberg et al, "Method to Map Antigenic Determinants . . . Protein Gp. 70" PNAS 81, 1984, pp. 3675-3679.
C. A. No. 108631z, vol. 101; Rothhard et al. (J. Exp. Med. 1984 160C.) pp. 208-221).
O'Hanley et al, Mannose-Sensitive and Gal-Gal Binding E. Coli pili . . . Strains, J. Exp. Med. 158, (1983), pp. 1713-1719.
C.A. No. 1068631z, Strain-specific and common epitopesz gondirecal pili, Jonathan et al. vol (101) 1984.
Rothhard et al, Current Communication in Molecular Biology, et Lauer et al, 1985, pp. 161-168.
Synthetic Peptides as Antigen, ed Porter et al., 1986, pp. 184-193 (varies).

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