Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Culture medium – per se
Reexamination Certificate
2005-10-27
2009-10-06
Barnhart, Lora E (Department: 1651)
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Culture medium, per se
C435S325000
Reexamination Certificate
active
07598083
ABSTRACT:
Chemically defined media compositions for the culture of eukaryotic cells are disclosed. The compositions are useful for eukaryotic cell culture in perfusion bioreactors and other vessels.
REFERENCES:
patent: 4282326 (1981-08-01), Moldenhauer et al.
patent: 4533637 (1985-08-01), Yamane et al.
patent: 4657866 (1987-04-01), Kumar et al.
patent: 4767704 (1988-08-01), Cleveland et al.
patent: 5045468 (1991-09-01), Darfler et al.
patent: 5393668 (1995-02-01), Cinatl et al.
patent: 6048728 (2000-04-01), Inlow et al.
patent: 6146873 (2000-11-01), Kistner et al.
patent: 6171825 (2001-01-01), Chan et al.
patent: 6358703 (2002-03-01), Cho et al.
patent: 6475725 (2002-11-01), Reiter et al.
patent: 2002/0115152 (2002-08-01), Cho et al.
patent: 2002/0182679 (2002-12-01), Reiter et al.
patent: 2003/0203448 (2003-10-01), Reiter et al.
patent: 0485689 (2001-10-01), None
patent: WO 03/00423 (1993-01-01), None
patent: WO 98/08934 (1998-03-01), None
patent: WO 03/046162 (2003-06-01), None
Kovár, J and Fran{hacek over (e)}k, F, Serum-free Medium for Hybridoma and Parental Myeloma Cell Cultivation: a Novel Composition of Growth-supporting Substances,Immunol. Lett., vol. 7, (1984), pp. 339-345.
Fran{hacek over (e)}k, F., “Starvation-induced Programmed Death of Hybridoma Cells: Prevention by Amino Acid Mixtures,”Biotechnol. Bioengin., vol. 45, (1995), pp. 86-90.
Fran{hacek over (e)}k, F. and {hacek over (S)}ramková, K. “Cell Suicide in Starving Hybridoma Culture: Survival-signal Effect of Some Amino Acids,”Cytotechnol., vol. 23, (1997), pp. 231-239.
Fran{hacek over (e)}k, F. et al., “Plant Protein Hydrolysates: Preparation of Defined Peptide Fractions Promoting Growth and Production in Animal Cell Cultures,”Biotechnol. Prog., vol. 16, (2000), pp. 688-692.
Fran{hacek over (e)}k, F. and Chládková-{hacek over (S)}ramková, K., “Apoptosis and Nutrition: Involvement of Amino Acid Transport System in Repression of Hybridoma Cell Death,”Cytotechnol., vol. 18, (1995), pp. 113-117.
Fran{hacek over (e)}k, F. and Dolníková, J., “Hybridoma Growth and Monoclonal Antibody Production in Iron-rich Protein-free Medium: Effect of Nutrient Concentration,”Cytotechnol., vol. 7, (1991), pp. 33-38.
Jo, E-C. et al., “Balanced Nutrient Fortification Enables High-density Hybridoma Cell Culture in Batch Culture,”Biotechnol. Bioengin., vol. 36, (1990), pp. 717-720.
Fran{hacek over (e)}k, F. and {hacek over (S)}ramková, K., “Protection of B Lymphocyte Hybridoma against Starvation-induced Apoptosis: Survival-signal role of Some Amino Acids,”Immunol. Lett., vol. 52, (1996), pp. 139-144.
Schneider, Y-J., “Optimization of Hybridoma Cell Growth and Monoclonal Antibody Secretion in a Chemically Defined, Serum- and Protein-free Culture Medium,”J. Immunol. Meth., vol. 116, (1989), pp. 65-77.
Keen, MJ., and Hale, C., “The Use of Serum-free Medium for the Production of Functionally Active Humanized Monoclonal Antibody from NS/0 Mouse Myeloma Cells Engineered Using Glutamine Synthetase as a Selectable Marker,”Cytotechnol., vol. 18, (1996) pp. 207-217.
Qi, YM. et al., “Evaluation of a Simple Protein-free Medium that Supports High Levels of Monoclonal Antibody Production,”Cytotechnol., vol. 21, (1996), pp. 95-109.
Fran{hacek over (e)}k, F. and {hacek over (S)}ramková, K. “Cell Suicide in Starving Hybridoma Culture: Survival-signal Effect of Some Amino Acids,”Cytotechnol., vol. 21, (1996), pp. 81-89.
Cleveland, WL. et al., “Routine Large-scale Production of Monoclonal Antibodies in a Protein-free Culture Medium,”J. Immunol. Meth., vol. 56, (1983), pp. 221-234.
Chen, Z. et al., “A Low-cost Chemically Defined Protein-free Medium for a Recombinant CHO Cell Line Producing Prothrombin,”Biotechnol. Lett., vol. 22, (2000), pp. 837-841.
Tang, X-h. and Shay, NF. “Zinc Has an Insulin-like Effect on Glucose Transport Mediated by Phosphoinositol-3-kinase and Akt in 3T3-L1 Fibroblasts and Adipocytes,”J.Nutrit., vol. 131, (2001), pp. 1414-1420.
Ezaki, O. “IIb Group Metal Ions (Zn+2, Cd+2, and Hg+2) Stimulate Glucose Transport Activity by Post-insulin Receptor Kinase Mechanism in Rat Adipocytes,”J.Biol.Chem. vol. 264, (1989) pp. 16118-16122.
May, JM. And Contoreggi, CS., “The Mechanism of the Insulin-like Effects of Ionic Zinc,”J.Biol.Chem., vol. 257, (1982), pp. 4362-4368.
Epstein David
Horwitz Joseph
Lenk Susan
Marsh Christopher
Monsell Roger
Barnhart Lora E
Baumeister Kirk
Centocor, Inc.
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