Chemical synthesis of S-adenosyl-L-methionine with...

Details Chemical synthesis of S-adenosyl-L-methionine with... Chemical synthesis of S-adenosyl-L-methionine with...

2005-04-19

2005-04-19

Wilson, James O. (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S127000

Reexamination Certificate

active

06881837

ABSTRACT:
This invention relates to the production of S-adenosyl-L-methionine by means of a chemical process wherein enrichment of the bioactive (S,S)-isomer is achieved. The process is simple, efficient, economical and reproducible on large scale.

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Matos, J. et al “S-Adenosylmethionine: Studies on Chemical and Enzymatic Synthesis” Biotechnol. Appl. Biochem. vol. 9, pp. 39-52, 1987.*
Ramalingam, K. “Preparation of S-(N,N-dimethyladenosyl)-L-methionine” Carbohyd. Res. vol. 142, pp. 123-126, 1985.

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