Chemical process for the preparation of pharmaceutically active

Details Chemical process for the preparation of pharmaceutically active Chemical process for the preparation of pharmaceutically active

1990-01-19

1991-06-11

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548329, C07D23530

Patent

active

050233378

ABSTRACT:
The present invention is directed to the preparation of benzimidazole derivatives of the formula (I), ##STR1## wherein A=stands for S, SO or SO.sub.2,

REFERENCES:
patent: 3325470 (1967-06-01), Ribka
Chemical Abstracts, 100: 174242 d (1984) [Valitov, F., Deposited Doc. 1982, Viniti 6343-82, 103-11].
Chemical Abstracts, 97:38617x (1982) [Alberola, A., et al., An. Quim. Ser. C. 1982, 78(1), 67-72].
Chemical Abstracts, 102:6257k(1985) [Alberola, A., et al., An. Quim. Ser. C, 1984, 80(1), 59-64].
Fiester, L. et al., Reagents for Organic Chemistry, John Wiley, New York, 1967, pp. 1179-1181.
March, J., Advance Organic Chemistry, McGraw Hill, New York, 1968, pp. 319-320 and 335.
Alberola, A., et al., Alkylaluminums, XXVII. Reaction of Carboxylic Acid Chlorides with Triphenylaluminum, An. Quim, Ser. C 1982, 78(1), pp. 67-72.
Alberola, A. et al., Behavior of 4-Alpha-Haloalkylisoxazoles Toward Organomagnesium and Organoaluminum Compounds, An. Quim. Ser. C, 1984, 80(1), pp. 59-64.
Valitov, F. H., Synthesis of Ketones from Aluminiumorganic Compounds and Chlorohydrides of Acids. U.S.S.R., Deposited Document 1982, This is the underlying reference in Chem. Abstracts 100:174242d (1984) cited by the Examiner as Chem Abstracts (.RTM.).

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