Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2011-01-04
2011-01-04
Andres, Janet L (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
active
07863469
ABSTRACT:
The present invention relates to compounds useful as pharmaceutical intermediates, to processes for preparing the intermediates, to intermediates used in the processes, and to the use of the intermediates in the preparation of pharmaceuticals. In particular, the present invention concerns enantiomerically pure trans-cyclopropane carboxylic acid derivatives, processes for preparing the carboxylic acid derivatives and their use in preparing pharmaceuticals.
REFERENCES:
patent: 4411925 (1983-10-01), Brennan et al.
patent: 4590292 (1986-05-01), Blackwell et al.
patent: 4933477 (1990-06-01), Goetz et al.
patent: 5225602 (1993-07-01), Hoelderich et al.
patent: 6552217 (2003-04-01), Hubbs et al.
patent: 6683216 (2004-01-01), Zoeller et al.
patent: 2008/0071114 (2008-03-01), Mitsuda et al.
patent: 3909142 (1990-10-01), None
patent: 4315623 (1994-11-01), None
patent: 19523868 (1997-01-01), None
patent: 0192263 (2001-12-01), None
Tomoskozi, Tetrahedron (1963), 19(12), 1969-1979, Abstract.
Armstrong et al., “Stereocontrolled synthesis of 3-(trans-2-aminocyclopropyl)alanine, a key component of belactosin A,” Organic Letters (2003) 5(13):2331-2334.
Barbieri et al., “Chemo-enzymatic synthesis of (R)-and (S)-3,4-dichlorophenylbutanolide intermediate in the synthesis of sertraline,” Tetrahedron: Asymmetry (1999) 10:3931-3937.
Singh et al., “Development of a practical, safe, and high-yielding process for the preparation of enantiomerically pure trans-cyclopropane carboxylic acid,” Organic Process Research & Development (2002) 6:618-620.
Office Action dated Mar. 20, 2009 received in copending U.S. Appl. No. 11/833,266.
Engel et al., J Org Chem (1988) 53(20):4748-4758.
Database CAPLUS on STN, Acc. No. 1971:435269, Filler et al., “,” J Chem Soc, Section C: Organic (1971) 11:2062-2068 (abstract).
Yasui et al., J Am Chem Soc (1987) 109(8):2311-2320.
Wang et al., “Enantioselective synthesis of chiral cyclopropane compounds through microbial transformations of trans-2-arylcyclopropanecarbonitriles,” Tetrahedron Letters (2000) 41:6501-6505.
White “New reactions of polyfluoroaromatic compounds. Part II. Polyfluoroaralkyl amines,” J. Chem Soc. (1971) 2062-2068.
Notice of copending applications.
Office Action dated Oct. 23, 2009 received in copending U.S. Appl. No. 11/833,266.
Notice of allowance dated May 6, 2010 received in copending U.S. Appl. No. 11/833,266.
Dejonghe Jean-Paul
Peeters Koen
Renard Marc
Andres Janet L
Astrazeneca AB
Gallis David E
Pepper Hamilton LLP
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