Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Reexamination Certificate
2005-03-30
2010-12-07
Henley, III, Raymond J (Department: 1614)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
Reexamination Certificate
active
07846973
ABSTRACT:
The present invention relates to the preparation of a β2adrenergic agonist in crystalline salt form. In particular the invention relates to preparation of a crystalline salt of compound (I)in particular a crystalline monohydrochloride salt. The invention also relates to a new crystalline form (polymorph) of the monohydrochloride salt of compound (Ia) and a process for preparing it.
REFERENCES:
patent: 4353656 (1982-10-01), Sohl et al.
patent: 4778054 (1988-10-01), Newell et al.
patent: 4811731 (1989-03-01), Newell et al.
patent: 5495054 (1996-02-01), Gao et al.
patent: 5552438 (1996-09-01), Christensen, IV
patent: 5590645 (1997-01-01), Davies et al.
patent: 5860419 (1999-01-01), Davies et al.
patent: 5873360 (1999-02-01), Davies et al.
patent: 6268533 (2001-07-01), Gao et al.
patent: 6321747 (2001-11-01), Dmitrovic et al.
patent: 6576793 (2003-06-01), Moran et al.
patent: 6632666 (2003-10-01), Baust et al.
patent: 069715 (1983-01-01), None
patent: 2064336 (1981-06-01), None
patent: 2129691 (1984-05-01), None
patent: 2169265 (1986-07-01), None
patent: 2178965 (1987-02-01), None
patent: 2242134 (1991-09-01), None
patent: 01/42193 (2001-06-01), None
patent: 03/042164 (2003-05-01), None
patent: 03/061743 (2003-07-01), None
patent: 2004/011416 (2004-02-01), None
patent: 2004/024728 (2004-03-01), None
patent: 2004/106279 (2004-12-01), None
Caira, “Crystalline polymorphism of organic compounds,”Topics in Current Chemistry198:163-208 (1998).
Gould, “Salt Selection for basic Drugs,”International Journal of Pharmaceutics33(1/3):201-217 (1986).
Hett et al., Large-scale synthesis of enantio- and diastereomerically pure (R,R)-formoterol,Organic Process Research&Development2(2):96-99 (Mar. 1998).
Hong et al., “cis-1-amino-2-indanol in asymmetric synthesis. Part 1. A practical catalyst system for the enantioselective borane reduction of aromatic ketones,”Tetrahedron Letters35(36):6631-6634 (Sep. 1994).
Caine Darren Michael
Paternoster Ian Leonard
Shapland Peter David Penberthy
Hagenah Jeffrey A.
Henley, III Raymond J
Saxon Roberta P.
Theravance Inc.
LandOfFree
Chemical process and new crystalline form does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Chemical process and new crystalline form, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chemical process and new crystalline form will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4182585