Chemical modification of granulocyte-colony stimulating factor (

Details Chemical modification of granulocyte-colony stimulating factor ( Chemical modification of granulocyte-colony stimulating factor (

1998-07-21

2000-01-25

Moezie, F. T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 2, 514 21, 530324, 530412, 530402, A61K 3816

Patent

active

060178760

ABSTRACT:
The present invention broadly relates to chemical modification of biologically active proteins or analogs thereof. More specifically, the present invention describes novel methods for site-specific chemical modification of various proteins, and resultant compositions having improved biocompatibility and bioactivity.

REFERENCES:
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patent: 4955857 (1990-09-01), Shettigar
patent: 5214132 (1993-05-01), Kuga et al.
patent: 5635180 (1997-06-01), Morgan, Jr. et al.
patent: 5677422 (1997-10-01), Safarian et al.
patent: 5900404 (1999-05-01), Gegg et al.
Holcenberg et al., The Journal of Biological Chemistry, vol. 250, No. 71, 4165-4170 (1975).

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