Chemical intermediate

Details Chemical intermediate Chemical intermediate

2008-01-01

2008-01-01

Habte, Kahsay (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

C514S230500

Reexamination Certificate

active

10532223

ABSTRACT:
Compounds of Formula I, wherein R2represents C1-6alkyl (optionally substituted by one or more substituents selected from —OH, halo, cyano, nitro and aryl) or aryl, wherein each aryl and aryloxy group, unless otherwise specified, is optionally substituted, and methods of preparation thereof are disclosed

REFERENCES:
patent: WO-01/28992 (2001-04-01), None
patent: WO-02/083690 (2002-10-01), None
Chapman et al., “Difluoramination of Heterocyclic Ketones: Control of Microbasicity,” J. Org. Chem. 63:1566-1570 (1998).
Chapman et al., “Nitrolysis of a Highly Deactivated Amide by Protonitronium. Synthesis and Structure of HNFX1,” J. Org. Chem. 64:960-965 (1999).
Dave et al., “Facile Preparation of 3,7-Diazabicyclo[3.3.0]octaine and 3,7,10Triheterocyclic [3.3.3]Propellane Ring Systems from 1,5-Diazacyclooctane 3,7-Derivatives1,” J. Org. Chem. 61:8897-8903 (1996).
Paudler et al., “3,7-Disubstituted Octahydro-1,5-diazocines. Their Conversion Into Tetrahydro-1,5-diazocines and into Ring-Contraced Products,” J. Org. Chem 32:2425-2430 (1967).
Paudler et al., “1,5-Bis(p-toluenesulfonyl)-3,7-Dihydroxyoctahydro-1,5-diazocine,” J. Org. Chem. 31:277-280 (1966).
Stetter et al., “Synthese des 1.3-Diaza-6-oxa-adamantans,” Chem. Ber. 96(11):2827-2831 (1963).
PCT/SE2003/001594 International Search Report (Jan. 12, 2004).

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