Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-11-13
2007-11-13
Seaman, Margaret D. (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S321000, C514S322000, C514S326000, C546S124000, C546S199000, C546S208000, C546S210000
Reexamination Certificate
active
10556023
ABSTRACT:
Compounds of formula (I): compositions comprising them, processes for preparing them and their use in medical therapy (for example modulating CCR5 receptor activity in a warm blooded animal)
REFERENCES:
patent: 3203992 (1965-08-01), Kunz et al.
patent: 3577432 (1971-05-01), Helsley et al.
patent: 3755584 (1973-08-01), Plotnikoff et al.
patent: 3818017 (1974-06-01), Janssen et al.
patent: 3894030 (1975-07-01), Janssen et al.
patent: 4029801 (1977-06-01), Cavalla et al.
patent: 4105666 (1978-08-01), Ward
patent: 4105771 (1978-08-01), Archibald et al.
patent: 4166119 (1979-08-01), Effland et al.
patent: 4246267 (1981-01-01), Vincent et al.
patent: 4264613 (1981-04-01), Regnier et al.
patent: 4338323 (1982-07-01), Regnier et al.
patent: 4367232 (1983-01-01), Boix-Igleasias et al.
patent: 5576321 (1996-11-01), Krushinski, Jr. et al.
patent: 5595872 (1997-01-01), Wetterau, II et al.
patent: 5614523 (1997-03-01), Audia et al.
patent: 5614533 (1997-03-01), Anderson et al.
patent: 5627196 (1997-05-01), Audia et al.
patent: 5688960 (1997-11-01), Shankar
patent: 5696267 (1997-12-01), Reichard et al.
patent: 5741789 (1998-04-01), Hibschman et al.
patent: 5789402 (1998-08-01), Audia et al.
patent: 5840725 (1998-11-01), Reichard et al.
patent: 6790854 (2004-09-01), Tsushima et al.
patent: 6958350 (2005-10-01), Brough et al.
patent: 6960602 (2005-11-01), Burrows et al.
patent: 7041667 (2006-05-01), Armour et al.
patent: 7192973 (2007-03-01), Tucker
patent: 2002/0094989 (2002-07-01), Hale et al.
patent: 2004/0006081 (2004-01-01), Burrows et al.
patent: 2004/0110952 (2004-06-01), Burrows et al.
patent: 2004/0122049 (2004-06-01), Burrows et al.
patent: 2004/0266823 (2004-12-01), Cumming et al.
patent: 2005/0014788 (2005-01-01), Cumming et al.
patent: 2005/0171353 (2005-08-01), Cumming
patent: 2005/0250792 (2005-11-01), Thom et al.
patent: 2006/0052413 (2006-03-01), Tucker
patent: 2006/0069120 (2006-03-01), Oldfield et al.
patent: 2006/0189650 (2006-08-01), Cumming et al.
patent: 37 23 568 (1989-01-01), None
patent: 197 03 131 (1998-07-01), None
patent: 197 55 268 (1999-06-01), None
patent: 0 077 427 (1983-04-01), None
patent: 0 095 454 (1983-11-01), None
patent: 0 128 007 (1984-12-01), None
patent: 0 228 893 (1987-07-01), None
patent: 0 235 463 (1987-09-01), None
patent: 0 290 958 (1988-11-01), None
patent: 0 354 568 (1990-02-01), None
patent: 0 407 217 (1991-01-01), None
patent: 0 445 862 (1991-09-01), None
patent: 0 457 686 (1991-11-01), None
patent: 0 496 691 (1992-07-01), None
patent: 0 587 311 (1994-03-01), None
patent: 0 625 507 (1994-11-01), None
patent: 0 643 057 (1995-03-01), None
patent: 0 722 941 (1996-07-01), None
patent: 0 903 349 (1999-03-01), None
patent: 1 013 276 (2000-06-01), None
patent: 1 277 737 (2003-01-01), None
patent: 2 096 916 (1972-03-01), None
patent: 2 190 430 (1974-02-01), None
patent: 1368012 (1974-09-01), None
patent: 1 404 868 (1975-09-01), None
patent: 1425354 (1976-02-01), None
patent: 1 532 671 (1978-11-01), None
patent: 1 538 542 (1979-01-01), None
patent: 1 544 191 (1979-04-01), None
patent: 63264525 (1988-11-01), None
patent: 10259176 (1998-09-01), None
patent: WO 92/02502 (1992-02-01), None
patent: WO 92/15579 (1992-09-01), None
patent: WO 93/13083 (1993-07-01), None
patent: WO 93/15052 (1993-08-01), None
patent: WO 93/25528 (1993-12-01), None
patent: WO 94/27967 (1994-12-01), None
patent: WO 95/11880 (1995-05-01), None
patent: WO 96/19452 (1996-06-01), None
patent: WO 96/26205 (1996-08-01), None
patent: WO 96/34857 (1996-11-01), None
patent: WO 96/39386 (1996-12-01), None
patent: WO 97/10207 (1997-03-01), None
patent: WO 97/10212 (1997-03-01), None
patent: WO 97/19060 (1997-05-01), None
patent: WO 97/23458 (1997-07-01), None
patent: WO 97/42956 (1997-11-01), None
patent: WO 97/47299 (1997-12-01), None
patent: WO 98/02151 (1998-01-01), None
patent: WO 98/08826 (1998-03-01), None
patent: WO 98/31364 (1998-07-01), None
patent: WO 98/31366 (1998-07-01), None
patent: WO 98/32442 (1998-07-01), None
patent: WO 98/51311 (1998-11-01), None
patent: WO 99/04794 (1999-02-01), None
patent: WO 99/17773 (1999-04-01), None
patent: WO 99/25686 (1999-05-01), None
patent: WO 99/27928 (1999-06-01), None
patent: WO 99/27929 (1999-06-01), None
patent: WO 99/28314 (1999-06-01), None
patent: WO 99/31092 (1999-06-01), None
patent: WO 99/37304 (1999-07-01), None
patent: WO 99/37619 (1999-07-01), None
patent: WO 99/38514 (1999-08-01), None
patent: WO 99/64394 (1999-12-01), None
patent: WO 99/65895 (1999-12-01), None
patent: WO 00/08013 (2000-02-01), None
patent: WO 00/21948 (2000-04-01), None
patent: WO 00/21952 (2000-04-01), None
patent: WO 00/23076 (2000-04-01), None
patent: WO 00/35449 (2000-06-01), None
patent: WO 00/35451 (2000-06-01), None
patent: WO 00/39108 (2000-07-01), None
patent: WO 00/53600 (2000-09-01), None
patent: WO 00/58305 (2000-10-01), None
patent: WO 00/61559 (2000-10-01), None
patent: WO 00/69820 (2000-11-01), None
patent: WO 00/76511 (2000-12-01), None
patent: WO 00/76512 (2000-12-01), None
patent: WO 00/76513 (2000-12-01), None
patent: WO 00/76514 (2000-12-01), None
patent: WO 00/76972 (2000-12-01), None
patent: WO 00/76973 (2000-12-01), None
patent: WO 01/14333 (2001-03-01), None
patent: WO 01/19817 (2001-03-01), None
patent: WO 01/43744 (2001-06-01), None
patent: WO 01/44227 (2001-06-01), None
patent: WO 01/66525 (2001-09-01), None
patent: WO 01/87839 (2001-11-01), None
patent: WO 01/90106 (2001-11-01), None
patent: WO 01/92227 (2001-12-01), None
patent: WO 02/066460 (2002-08-01), None
patent: WO 02/070479 (2002-09-01), None
patent: WO 02/076948 (2002-10-01), None
patent: WO 02/079156 (2002-10-01), None
patent: WO 03/030898 (2003-04-01), None
patent: WO 03/042177 (2003-05-01), None
patent: WO 03/042178 (2003-05-01), None
patent: WO 03/042205 (2003-05-01), None
patent: WO 03/080574 (2003-10-01), None
patent: WO 2004/056773 (2004-07-01), None
patent: WO 2004/056808 (2004-07-01), None
patent: WO 2004/056809 (2004-07-01), None
Hariharan et al., “Interferon-γ Upregulates CCR5 expression in cord and adult blood mononuclear phagocytes”, Blood, 1999, vol. 93, pp. 1137-1144.
Balashov et al., “CCR5+ and CXCR3+ T cells are increased in multiple sclerosis and their ligands MIP-1α and IP-10 are expressed in demyelinating brain lesions”, Proc. Natl. Acad. Sci., 1999, vol. 96, pp. 6873-6878.
Zhang et al., “Synthesis and biological evaluation of tropane-like 1-{2-[Bis(bis(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine (GBR 12909) analogues”, J. Med. Chem., vol. 44, 3937-3945, 2001.
McGaw, “What it means when an examiner says ‘election of species requirement’”, Smith & Hopen Article ID:37 (2005), available online at http://www.smithhopen.com/faq—display.asp?faz—id=37.
Mensonides-Harsema et al., “Synthesis and in Vitro and in Vivo Functional Studies ofOrtho-Substituted Phenylpiperazine andN-Substituted 4-N-(o-Methoxyphenyl)aminopiperidine Analogues of WAY100635”,J. Med. Chem. 43:432-439 (2000).
Meurer et al., “Discovery of potent human CCR5 antagonists for the treatment of HIV˜1 infection—II.”CAPLUS2000:331722 (2000).
Navas III et al., “The Design and Synthesis of a Hapten for 1192U90, A Potential Atypical Antipsychotic Agent”,Synthetic Communications26(7):1411-1421 (1996).
Naya et al., “Design, Synthesis, and Discovery of a Novel CCR1 Antagonist”,J. Med. Chem. 44:1429-1435 (2001).
Ng et al., “Discovery of Novel Non-Peptide CCR1 Receptor Antagonists”,J. Med. Chem. 42:4680-4694 (1999).
Patent Abstracts of Japan, Medicine Composition Containing Piperazine Derivative and Having Active Oxygen Production Inhibiting And Active Oxygen Removing Action (Nov. 1, 1988).
Payard et al., “N-Aminomethylated Derivatives of Some Hydroxamic Acids as Anti-Inflammatories”,Eur. J. Med. Chem. pp. 1-10 (1975).
Rollins, “Chemokines”,Blood90(3):909-928 (1997).
Rubini et al., “Synthesis of Isosteric Methylene-Oxy Pseudodipeptide Analogues as Novel Amide Bond Surrogate Un
Cumming John
Faull Alan
AstraZeneca AB
Fish & Richardson P.C.
Rahmani Niloofar
Seaman Margaret D.
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