Chemical compounds

Details Chemical compounds Chemical compounds

2005-12-20

2005-12-20

Chang, Celia (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S320000, C514S324000, C514S326000, C514S330000, C546S193000, C546S196000, C546S202000, C546S214000, C546S226000

Reexamination Certificate

active

06977263

ABSTRACT:
Provided herein are novel and useful compounds having a tryptase inhibition activity, pharmaceutical compositions comprising such compounds, and methods treating subjects suffering from a condition, disease, or disorder that can be ameliorated by the administration of an inhibitor of tryptase, e.g., asthma and inflammatory diseases, to name only a few.

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patent: 5442064 (1995-08-01), Pieper et al.
patent: 5629321 (1997-05-01), Okumura et al.
patent: 6812236 (2004-11-01), Gibson et al.
patent: 2002/0045613 (2002-04-01), Pauls et al.
patent: 2002/0055522 (2002-05-01), Liebeschuetz et al.
patent: 2002/0099216 (2002-07-01), Gibson et al.
patent: 2005/0085456 (2005-04-01), Gibson et al.
patent: 1 072 592 (2001-01-01), None
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Pieper et al. Preparation of diazine-containing . . . CA 122:290875 (1995).
Barbachyn et al. “Preparation of isoxazolines as antimicrobials” CA 128:192646 (1998).
CAS structure for US 5,442,064 (1995).

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